ID A0A2D0QXP7_ICTPU Unreviewed; 749 AA.
AC A0A2D0QXP7;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=DNA-binding protein RFX2 {ECO:0000256|ARBA:ARBA00039910};
DE AltName: Full=Regulatory factor X 2 {ECO:0000256|ARBA:ARBA00042136};
GN Name=rfx2 {ECO:0000313|RefSeq:XP_017322526.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017322526.1};
RN [1] {ECO:0000313|RefSeq:XP_017322526.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017322526.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_017322526.1; XM_017467037.3.
DR AlphaFoldDB; A0A2D0QXP7; -.
DR GeneID; 108264993; -.
DR CTD; 5990; -.
DR OrthoDB; 2915941at2759; -.
DR Proteomes; UP000221080; Chromosome 5.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003150; DNA-bd_RFX.
DR InterPro; IPR039779; RFX-like.
DR InterPro; IPR007668; RFX1_trans_act.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12619:SF17; DNA-BINDING PROTEIN RFX2; 1.
DR PANTHER; PTHR12619; RFX TRANSCRIPTION FACTOR FAMILY; 1.
DR Pfam; PF04589; RFX1_trans_act; 1.
DR Pfam; PF02257; RFX_DNA_binding; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51526; RFX_DBD; 1.
PE 4: Predicted;
KW Cilium biogenesis/degradation {ECO:0000256|ARBA:ARBA00022794};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125,
KW ECO:0000313|RefSeq:XP_017322526.1}.
FT DOMAIN 221..296
FT /note="RFX-type winged-helix"
FT /evidence="ECO:0000259|PROSITE:PS51526"
SQ SEQUENCE 749 AA; 84063 MW; 603471D08DD7D755 CRC64;
MSFLRFARCP EKLKDSRSPA RRCQIVVEVR QHSQTHPLKR ERENIMQNSE GGSEAAATVA
LQTTTSAQAP VVQPVPPSQQ RVLVQATGSS PKPQVQQLSR VQQVPQQVQH VQHVYPTQVQ
YVEGGETIYP NGTIRTAYTY NHDAQLYGQA SGNSYFDTQA GATQVTTVVS SASSVPSHSM
VGIAMDVGGS HVISSSGAYL IHGGMDGRHH ATPSSRSSSA MLQWLLDNYE TAEGVSLARC
SLYNHYLRHC HEQKLDPVNA ASFGKLIRSV FMGLRTRRLG TRGNSKYHYY GIRVKPDSPL
NQMQDDTQYM AMRQQPIHHK QRFKPLQKMG GMSDCISFGS QHSSSTPEQS VAAQSQHHQQ
YIDVSHALPP FPSLELDSCP LPERITMNDV KKLQSIYRDH CEATLDVVMN LQFHFIEKLW
QTFWYSALPS SDGSTTTIPS SDEELEGVIP REKLIALCKF EPVKQWMRSC DHILYQALVE
ILIPDVLRPV PSTLTQAIRN FAKSLEGWLT SAMSNFPQEI VRTKAAVVSA FAQTLRRYTS
LNHLAQAARA VLQNTSQINQ MLSDLNRVDF ANVQEQASWV CQCDESVVQR LEQDFKMTLQ
QQSSLDQWAA WLDSVVSQVL KPHEGSPSFP RAARQFLLKW SFYSSMVIRD LTLRSAASFG
SFHLIRLLYD EYMFYLVEHR VALATGETPI AVMGEFNDHS LMMPSLMEKD ASFSDDMSDL
GSDADVSRGT CEPTVKSERI EINHTLQEI
//
