ID A0A2D0R4I8_ICTPU Unreviewed; 732 AA.
AC A0A2D0R4I8;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2023, sequence version 2.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Protein FAM171B {ECO:0000313|RefSeq:XP_017324715.2};
GN Name=LOC108266187 {ECO:0000313|RefSeq:XP_017324715.2};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017324715.2};
RN [1] {ECO:0000313|RefSeq:XP_017324715.2}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017324715.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the FAM171 family.
CC {ECO:0000256|ARBA:ARBA00006818}.
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DR RefSeq; XP_017324715.2; XM_017469226.3.
DR AlphaFoldDB; A0A2D0R4I8; -.
DR Ensembl; ENSIPUT00000009661; ENSIPUP00000009256; ENSIPUG00000006308.
DR KEGG; ipu:108266187; -.
DR OrthoDB; 4260817at2759; -.
DR Proteomes; UP000221080; Chromosome 6.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR018890; FAM171.
DR InterPro; IPR049175; FAM171_C.
DR InterPro; IPR048530; FAM171_N.
DR PANTHER; PTHR31626:SF2; PROTEIN FAM171B; 1.
DR PANTHER; PTHR31626; SUSHI DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF20771; FAM171A1-2-B_C; 1.
DR Pfam; PF10577; FAM171A1-2-B_N; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..732
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039950878"
FT TRANSMEM 335..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 67..313
FT /note="FAM171 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10577"
FT DOMAIN 516..732
FT /note="FAM171 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF20771"
FT REGION 371..415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 675..732
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 383..398
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 718..732
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 732 AA; 81469 MW; 37198ACC5CFE6ACB CRC64;
MDKLTMLLFL LTLFIFSKDG RVTAGFKGSA RASLTLIDGT QDQLAYHHNH QDNHDGGFSG
QEGSTFTLRV QVKNAVSQQP LSHASVEVFV NYTLINSTMT GRDGVTVLRV PYTHSWPLML
VARKDGYIQT PLLWKTTKIP IFSSVTLPLF YQNQGNIWLF EDLVIITGKM SDTVPPANVQ
FPKRLLTLPD NNISSITAYL TVPRLPVEKH FFPNTTGIIM SKSGFRSVEL NPIAAVSVQL
LYNGIDVQIS GPVQITLPLA ESSQSQLSYT VPAWSFDRKT GVWVNRGLGT VQMENRHLVW
VYTAPHLDYW IAAPFPSSTG YMGHESPLDF ISYNAYLLIP VVGGGLIIAV GLLAVVSCYC
RDSLCKRKRK RVHSRKTAVQ KKDQTTGRNN SNEQLDISFK PPTHKHRHRS AAFQSTSVCK
RDHENLAKTS QESTKTLETP QNVNSSELVI PVSLHENVCL PESLVLYNQS VALIQVPHHV
TSSDQASGSR SATLPRKAVQ YSGLEKPKMA LLSDFKQQDI TMEMTYEEPR AKGWSCLLES
VSVPDTLNKA TGMDTSCGTN QGSSEQTLLE LSKNKPFPHP KAWFVSLEGK PAAQVCHSIV
DLRKCHLLLT DSQDTSLDSG VDLNEQHQKQ NQSYLKRNTA HTQAIYSENA DLSSCESGTI
IACTPEELLL KNTHQSSGGT VSYLPEEKCD DDTSYEGSEC APSPRVQRLR KAKEKPKSTW
HRREERPLMK LN
//
