ID A0A2D0R7G1_ICTPU Unreviewed; 955 AA.
AC A0A2D0R7G1;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2023, sequence version 2.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Aryl hydrocarbon receptor {ECO:0000313|RefSeq:XP_017325760.2};
GN Name=LOC108266654 {ECO:0000313|RefSeq:XP_017325760.2};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017325760.2};
RN [1] {ECO:0000313|RefSeq:XP_017325760.2}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017325760.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_017325760.2; XM_017470271.2.
DR AlphaFoldDB; A0A2D0R7G1; -.
DR STRING; 7998.ENSIPUP00000005164; -.
DR Ensembl; ENSIPUT00000005387; ENSIPUP00000005164; ENSIPUG00000002619.
DR KEGG; ipu:108266654; -.
DR OrthoDB; 5360131at2759; -.
DR Proteomes; UP000221080; Chromosome 6.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0030522; P:intracellular receptor signaling pathway; IEA:UniProt.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006805; P:xenobiotic metabolic process; IEA:InterPro.
DR CDD; cd19696; bHLH-PAS_AhR_like; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR039091; AHR/AHRR.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR013655; PAS_fold_3.
DR PANTHER; PTHR10649; ARYL HYDROCARBON RECEPTOR; 1.
DR PANTHER; PTHR10649:SF17; ARYL HYDROCARBON RECEPTOR; 1.
DR Pfam; PF00010; HLH; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08447; PAS_3; 1.
DR SMART; SM00353; HLH; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50888; BHLH; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Receptor {ECO:0000313|RefSeq:XP_017325760.2}.
FT DOMAIN 22..75
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT DOMAIN 111..174
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 955 AA; 106973 MW; A3ED91B28AB77533 CRC64;
MLDNDRYAGK KRKKPVQKQK PATDATKSNP SKRHRDRLNG ELDRLTNMLP FSENVCTRLD
KLSVLRLSVG YLKVKSFFNA TMRKNSAEFL TVNGLDTSKM DTMGFSEGDL LLQALNGFVL
VVTAEGYVFY TSPTIQDYLG FHQSDMIHQS VFEFIHIDDR AMFRRQLHFA LNPTLLNVEA
DGTQNSSDIT RNIVTYDPQH IPPENSSFLE RSFVCRFRCL LDNSSGFLKL NFQGRLKFLL
GQNRKAEDGS LVQPQLSLFA IATPVQPSAI LEIRTKTLIF QTKHKLDFTP MGIDSRGKVV
LGYTEMELCM RGSGYQFIHA ADMMHCADNH VRMIKTGESG MTVFRLLTKN GGWVWVQANA
RLVYKGGRPD FIIARQRALV NAEGEEHLRQ RRMQLPFSFT TGEAVLYNTC PMLDMTNLKD
TNGVTQKTLV PSSILDSMQK QDKSIYHQDT KPQFTEDDAF MDSWALFNVP NHTVQDETVN
EEDTVGSMID TLEQLAHNGD LCTALQQMEV DTADLKEWEN ALLRMTKDSN GNDRPLSLDE
ILTNDIFSYV EDALYKDNNT SCLSQPNAIK TDPFGGHSTT TVHSGCDFTH YNFDSEGADK
NDLKADRKLN SIAVTGQQMD RMVGTDATMG NKVPWYSDKS SQDHLNNSSH SEQTGLFIRD
SKVSQLITQT EMHLGLKVTQ NIFNIVPFNG WGPLKPTENG RTSKLESTES YCQFASYPTN
NTKNPQMNHA PNHIHKLSQT TTNLWNNMST GDRNLSLIPS KNCVSSIINC SNLSKFPQQR
QIQAWQNASP EQPCASLVKN RLASEGCYHT LETPGFPPSD LLPEISQSCN DKHINFISNV
YQSPQNGLSS KECSPLSSCM FENHSPLSTN ADQQHPQAQA VTISSCSKST LPINQSPPQA
SCYFQWACSE PLVGTSSIPQ EDTCISPPSC QIGPGIATLD SHSVFQRYLD CNGHV
//
