ID A0A2D0RF56_ICTPU Unreviewed; 349 AA.
AC A0A2D0RF56;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Interferon regulatory factor 2 isoform X3 {ECO:0000313|RefSeq:XP_017329174.1};
GN Name=irf2b {ECO:0000313|RefSeq:XP_017329174.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017329174.1};
RN [1] {ECO:0000313|RefSeq:XP_017329174.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017329174.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_017329174.1; XM_017473685.3.
DR AlphaFoldDB; A0A2D0RF56; -.
DR STRING; 7998.ENSIPUP00000030423; -.
DR Ensembl; ENSIPUT00000031648; ENSIPUP00000030423; ENSIPUG00000020557.
DR GeneID; 108268627; -.
DR CTD; 494071; -.
DR OMA; NFRITTV; -.
DR OrthoDB; 3740806at2759; -.
DR Proteomes; UP000221080; Chromosome 8.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR CDD; cd00103; IRF; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR019817; Interferon_reg_fac_CS.
DR InterPro; IPR001346; Interferon_reg_fact_DNA-bd_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11949; INTERFERON REGULATORY FACTOR; 1.
DR PANTHER; PTHR11949:SF22; INTERFERON REGULATORY FACTOR 2; 1.
DR Pfam; PF00605; IRF; 1.
DR PRINTS; PR00267; INTFRNREGFCT.
DR SMART; SM00348; IRF; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00601; IRF_1; 1.
DR PROSITE; PS51507; IRF_2; 1.
PE 4: Predicted;
FT DOMAIN 14..122
FT /note="IRF tryptophan pentad repeat"
FT /evidence="ECO:0000259|PROSITE:PS51507"
FT REGION 124..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 208..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 299..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 124..144
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 148..164
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 208..232
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 349 AA; 38925 MW; F30B4B1CCCD8F5F8 CRC64;
MLLTDDTATM PVERMRMRPW LEEQINSGKI PGLKWVHREK KIFQIPWMHA ARHGWDVEKD
APLFRNWAIH TGKYQPGVDK PDPKTWKANF RCAMNSLPDI EEVKDKSIKK GTNAFRVYKM
LSASERQSKR GKKRPDKDVK VKDEQQCPVS SAWESTNGST RSAGALAVKQ EADHTVTETE
AGSHSPSEDH LIIPDVCQTI EVVTENEEQA VSSSHTYPLQ ISPMSSYGES DTDSVQSEED
SKERMRALVW ASNHAEAKPA LDSSAMRTSL PSMSTFITQS KPNFRITTVQ DASSTPFHGP
YTSGGPWSLL ATPHPPSQPP AVSSKPPVHE KRASVIMKTS DVSKSVKSY
//
