ID A0A2D0RKS7_ICTPU Unreviewed; 319 AA.
AC A0A2D0RKS7;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Ankyrin repeat and SOCS box protein 12b isoform X1 {ECO:0000313|RefSeq:XP_017330746.1, ECO:0000313|RefSeq:XP_047012995.1};
GN Name=asb12b {ECO:0000313|RefSeq:XP_017330746.1,
GN ECO:0000313|RefSeq:XP_047012995.1, ECO:0000313|RefSeq:XP_053538131.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017330746.1};
RN [1] {ECO:0000313|RefSeq:XP_017330746.1, ECO:0000313|RefSeq:XP_047012995.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017330746.1,
RC ECO:0000313|RefSeq:XP_047012995.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR RefSeq; XP_017330746.1; XM_017475257.3.
DR RefSeq; XP_017330747.1; XM_017475258.1.
DR RefSeq; XP_017330748.1; XM_017475259.1.
DR RefSeq; XP_017330749.1; XM_017475260.1.
DR RefSeq; XP_047012995.1; XM_047157039.2.
DR RefSeq; XP_053538131.1; XM_053682156.1.
DR GeneID; 108269406; -.
DR KEGG; ipu:108269406; -.
DR CTD; 445507; -.
DR OrthoDB; 5475985at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000221080; Chromosome 8.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd03587; SOCS; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001496; SOCS_box.
DR PANTHER; PTHR24201; ANK_REP_REGION DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24201:SF14; ANK_REP_REGION DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR SMART; SM00248; ANK; 5.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 4.
DR PROSITE; PS50225; SOCS; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 68..100
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 101..133
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 134..166
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 176..208
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 266..319
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 319 AA; 35658 MW; 6C227A214EE2466F CRC64;
MMLDTSTKMS LMDITKIFSL LRPKEDEDED GCQQLNKAIA EDDDQLLADL LSQERYRRCI
NSRSGWGIPS TPLKTAAAHG HLRCLERLLA HGAEVDSLDV KAQTPLFTAV SGKHLGCVSA
LLKAGADPNG SQYNNCSPLL TAAREGDVDI LKELLYYGAE TDVQAKVPDW ASNATTCRGP
LYIAAVYGHL DCFKLLLLHG ADPDYNCKDK KILARIKRSN TVLDTCLKYG CQSEYIQLLI
DFGANIYIPV VITEKTREQD QVIKLLLRER VFLFAVCPKT LMSQIRLAIR KYLSAAHKLD
LIDELDIPQM LKNYLKHTT
//
