ID A0A2D0RU97_ICTPU Unreviewed; 314 AA.
AC A0A2D0RU97;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Docking protein 4 {ECO:0000313|RefSeq:XP_017334067.1, ECO:0000313|RefSeq:XP_017334068.1};
GN Name=dok4 {ECO:0000313|RefSeq:XP_017334067.1,
GN ECO:0000313|RefSeq:XP_017334068.1, ECO:0000313|RefSeq:XP_017334069.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017334069.1};
RN [1] {ECO:0000313|RefSeq:XP_017334067.1, ECO:0000313|RefSeq:XP_017334068.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017334067.1,
RC ECO:0000313|RefSeq:XP_017334068.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the DOK family. Type B subfamily.
CC {ECO:0000256|ARBA:ARBA00006520}.
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DR RefSeq; XP_017334067.1; XM_017478578.3.
DR RefSeq; XP_017334068.1; XM_017478579.3.
DR RefSeq; XP_017334069.1; XM_017478580.3.
DR STRING; 7998.ENSIPUP00000007791; -.
DR Ensembl; ENSIPUT00000008116; ENSIPUP00000007779; ENSIPUG00000005362.
DR Ensembl; ENSIPUT00000008129; ENSIPUP00000007791; ENSIPUG00000005362.
DR GeneID; 108271197; -.
DR KEGG; ipu:108271197; -.
DR CTD; 55715; -.
DR OMA; KMLSIEC; -.
DR OrthoDB; 2996885at2759; -.
DR Proteomes; UP000221080; Chromosome 10.
DR CDD; cd14678; PH_DOK4_DOK5_DOK6; 1.
DR CDD; cd13164; PTB_DOK4_DOK5_DOK6; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR InterPro; IPR037816; DOK4/5/6_PH.
DR InterPro; IPR002404; IRS_PTB.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR21258:SF44; DOCKING PROTEIN 4; 1.
DR PANTHER; PTHR21258; DOCKING PROTEIN RELATED; 1.
DR Pfam; PF02174; IRS; 1.
DR SMART; SM01244; IRS; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00310; PTBI; 1.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR PROSITE; PS51064; IRS_PTB; 1.
PE 3: Inferred from homology;
FT DOMAIN 132..237
FT /note="IRS-type PTB"
FT /evidence="ECO:0000259|PROSITE:PS51064"
FT REGION 280..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 280..297
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 300..314
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 314 AA; 35903 MW; 2EDF70991B6490B1 CRC64;
MASNFNDIVK QGYVRMRSRK LGIYRRCWLV FKKSSSKGPR RLEKYPDEKS AFIRVCPKVT
EISNVKNVTR LPRDTKRQAV AIVFTDDTSR MFTCESELEA EEWFKTLTIE CLGTRLNDIS
LGEPDLLAAG VQCEHTERFN VFLLPCPNLD IYGECMMQIT HENIYLWDIH NPRTKLVTWP
LCSLRRYGRD ATRFTFEAGR MCDSGEGLYT FQTREGEQIY QRVHSSTLAI AEQHKKVLME
MEKNSRLLSQ GSDPDSYPCT PTAILPRSAF WHHITGSQGA VDSSNGEMFT ASPSGAESDL
FSAEHHKHPA HFST
//
