ID   A0A2D0RUD0_ICTPU        Unreviewed;       976 AA.
AC   A0A2D0RUD0;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 isoform X2 {ECO:0000313|RefSeq:XP_017334107.1};
GN   Name=ppp4r1 {ECO:0000313|RefSeq:XP_017334107.1};
OS   Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC   Ictaluridae; Ictalurus.
OX   NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017334107.1};
RN   [1] {ECO:0000313|RefSeq:XP_017334107.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_017334107.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_017334107.1; XM_017478618.3.
DR   AlphaFoldDB; A0A2D0RUD0; -.
DR   STRING; 7998.ENSIPUP00000036313; -.
DR   Ensembl; ENSIPUT00000037737; ENSIPUP00000036313; ENSIPUG00000024324.
DR   GeneID; 108271209; -.
DR   CTD; 9989; -.
DR   OrthoDB; 1367932at2759; -.
DR   Proteomes; UP000221080; Chromosome 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000357; HEAT.
DR   InterPro; IPR021133; HEAT_type_2.
DR   InterPro; IPR033461; WRNPLPNID.
DR   PANTHER; PTHR10648; SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT; 1.
DR   PANTHER; PTHR10648:SF8; SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 1; 1.
DR   Pfam; PF02985; HEAT; 2.
DR   Pfam; PF15017; WRNPLPNID; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50077; HEAT_REPEAT; 3.
PE   4: Predicted;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REPEAT          156..195
FT                   /note="HEAT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT   REPEAT          236..274
FT                   /note="HEAT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT   DOMAIN          495..549
FT                   /note="Putative WW-binding"
FT                   /evidence="ECO:0000259|Pfam:PF15017"
FT   REPEAT          692..730
FT                   /note="HEAT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT   REGION          332..367
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          423..480
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          521..541
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          608..643
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        439..457
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        526..541
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        609..626
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        627..642
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   976 AA;  109199 MW;  49417CCB0004AD23 CRC64;
     MADISLLQED SQEEIDGSLD FVSQDEMLTP LGRLDKYVTS ENIFNRQMVA RSLLDTLKAV
     SEDERDCIAV LERVSRLAED SEPTVRAELM EQIPHIAIFC QDNRPSIPFA FSKYLLPIVV
     RYLADQNNLV RKTSQAALLM LLEQELIERA DIENLVCPVL VDLTAPDSND DVKTEAMAII
     CKMAPMVGKD ITERLFLPRF CEMCCDCRMF HVRKVCAANF GDICTVVGGE TTEELLLPRF
     FQLCSDNVWG VRKACAECFM TVSSATSQEV RRTKLASLFI NLISDPSRWV RQAAFQSLGQ
     FISTFASPST NVGQYFKEGT EEADWRGQQL HNRAGEKSMS SKAPATEESA QSPPCDEKAV
     SSQPDCISQN PPCTQENCEG QLCQSEREGV DVAVEGGGEQ AAEALPLDES CCHVDTDRHS
     PKCLSELGDL DPDQSAKEPH CSPATNPAAQ GSPSDTSEGP VMEKPAHSNP DGSSEVTCSA
     LPSNVTGKVE IPEQEQYNSF HYWRTPIPQI DLDLELSEEK CNSDDEVSAA SSSTQGSTSA
     LDRKQLEELI ENLEPHIDDP DVKAQVDVLT AALRATSLDT HVEEAFLEPR QAHDNPFSSC
     HVPLIDSSDV ESRESTLPVS HADDSELSDS SSPEDEKKSK QQDVVPQALL DQYLSMTDPS
     RAQTVDMEIA KHCAYSLPGV ALTLGRQNWH CLRDTFETLA SDMQWKVRRT LAFSIHELAL
     ILGDQLTAED LVPIFNGFLK DLDEVRIGVL RHLYDFLKLL HQDTRRKYLY QLQEFLVTDN
     SRNWRFRSEL AEQLVLLLEL YSGQDVYDYL RPLAFCLCID RVSSVRWTSY RLVSEIIRKL
     STYPALLVDF LGELVDKFCH SSKWSGRQAF AFVCQLAIEE DCVSLDQFSE HLLAPLLQLA
     SDPVPNVRVL LAKTLRQSLM EREYFLHSAN SHQEALEQTL VALQMDMDKD VKYFASIHPG
     STRINEDAMS TTSSTY
//