ID A0A2D0RUD5_ICTPU Unreviewed; 568 AA.
AC A0A2D0RUD5;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=FERM domain-containing protein 5 {ECO:0000313|RefSeq:XP_017334112.1};
GN Name=frmd5b {ECO:0000313|RefSeq:XP_017334112.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017334112.1};
RN [1] {ECO:0000313|RefSeq:XP_017334112.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017334112.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_017334112.1; XM_017478623.3.
DR AlphaFoldDB; A0A2D0RUD5; -.
DR STRING; 7998.ENSIPUP00000031155; -.
DR Ensembl; ENSIPUT00000032403; ENSIPUP00000031155; ENSIPUG00000020998.
DR GeneID; 108271218; -.
DR KEGG; ipu:108271218; -.
DR CTD; 569968; -.
DR OMA; IKWNEVA; -.
DR OrthoDB; 2912597at2759; -.
DR Proteomes; UP000221080; Chromosome 10.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd17102; FERM_F1_FRMD3; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR000798; Ez/rad/moesin-like.
DR InterPro; IPR014847; FA.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR PANTHER; PTHR23280:SF5; FERM DOMAIN-CONTAINING PROTEIN 5; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PRINTS; PR00935; BAND41.
DR PRINTS; PR00661; ERMFAMILY.
DR SMART; SM00295; B41; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 504..526
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 17..298
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 345..366
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 568 AA; 65046 MW; 5801169EA23D1115 CRC64;
MLSRVLSGSV RSLDREFNCT VRLLDDTEYT CTVQRDAKGR WIFEQICHHL SLLEKDYFGI
RYVDPEKQRH WLELNKPITK QMRSQPPFIM CLRVKFYPPD PAALKEEITR YLVFLQIKRD
LYHGRLLCKS SDAALLAAHI LQAETGDYTP EKHPEGYSSK FQFFPKHSER LERRIAEIHK
TELIGQTPET SELNFLRKAK TLEMYGVDPH PCKDVSGNAA FLGFTPSGFV VLQGNRRVHF
LKWNEVTKMK FEGKTFHIYA NQQEDQNIIL TYFAPTPEAC KHLWKCGVEN QAFYQFEKSS
QVRTVSSSNL FFKGSRFRYS GKVAKEVMEQ SAKIRRAPPE IHRAGMVPSR SCPSIAHGPR
QSSVPRTCRR AVHMSIMEGL ESLRDSGHST PVRSISHGHS LLRSHSNCAE GRNGASEFSE
ELYKPTDSVL PTPFSSNCSL DQALCQHMNS PPSVQEEKKT EAVIPKSGRL VVAKFTERVY
HLGKIQTPTG SMEVKQVSKV IGSLARLFLV TLTLLLALLL LLIALTESEL DVAFLRDIRQ
TAEFQQFHNE YFCPLRRWLA YKLRWMGG
//
