ID A0A2D0RYB4_ICTPU Unreviewed; 835 AA.
AC A0A2D0RYB4;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=RNA-binding protein 5 isoform X1 {ECO:0000313|RefSeq:XP_017335493.1};
GN Name=rbm5 {ECO:0000313|RefSeq:XP_017335493.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017335493.1};
RN [1] {ECO:0000313|RefSeq:XP_017335493.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017335493.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_017335493.1; XM_017480004.3.
DR AlphaFoldDB; A0A2D0RYB4; -.
DR STRING; 7998.ENSIPUP00000000897; -.
DR Ensembl; ENSIPUT00000000957; ENSIPUP00000000897; ENSIPUG00000000640.
DR GeneID; 108271979; -.
DR KEGG; ipu:108271979; -.
DR CTD; 10181; -.
DR OMA; CESEHER; -.
DR OrthoDB; 298711at2759; -.
DR Proteomes; UP000221080; Chromosome 11.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12755; RRM2_RBM5; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 4.10.1060.10; Zinc finger, RanBP2-type; 1.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR041591; OCRE.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR034993; RBM5_RRM2.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR001876; Znf_RanBP2.
DR PANTHER; PTHR13948; RNA-BINDING PROTEIN; 1.
DR PANTHER; PTHR13948:SF21; RNA-BINDING PROTEIN 5; 1.
DR Pfam; PF01585; G-patch; 1.
DR Pfam; PF17780; OCRE; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF00641; zf-RanBP; 1.
DR SMART; SM00443; G_patch; 1.
DR SMART; SM00360; RRM; 2.
DR SMART; SM00547; ZnF_RBZ; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50174; G_PATCH; 1.
DR PROSITE; PS50102; RRM; 2.
DR PROSITE; PS01358; ZF_RANBP2_1; 1.
DR PROSITE; PS50199; ZF_RANBP2_2; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}; Zinc {ECO:0000256|PROSITE-ProRule:PRU00322};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00322}.
FT DOMAIN 106..186
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 189..218
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 239..323
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 666..696
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 763..809
FT /note="G-patch"
FT /evidence="ECO:0000259|PROSITE:PS50174"
FT REGION 1..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 534..562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 627..659
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 694..728
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 546..562
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 835 AA; 93199 MW; 82D0C8D29B9B707E CRC64;
MGADKRVSRT ERSGRYGSEQ SRDDDRRDRR DRDDRVYDSH RWSDDRRSDR YDGDRGDRSD
RYWSRDSPER GRKRRSSDCS EDGHHSDGDY SEHDYRGDPA DEKESKTIML RGLPVNITET
DIRAAIDQLE GPQPMDVRLM KKRTGISRGF AFVEFYHLQD ATRWMETNQK LLTIQGKTVA
MHYSNTRHKF EDWLCNSCGL YNFRRRLKCF RCGAAKSDSD SSGTAGTTET QPSGDYYGDT
IILRNIAPLS TVEGIMASLA PYANLSPSNI RLIKDKQTGQ NRGFAFVQLS SPLEASQLLT
ILQGLQPPLK LDGKTIGVDY AKSARKDLLL PDGNRISAFS VASTAIAAAQ WSSSQPQQSV
DPASEYSYLQ EGYVPYSQEY QAQYQQQAGA TDPSQANGIL GAAPGMKILP TAGAVVISQG
AQVYQPHIIS QPATQTLQTM QTATITAAAT ISAPATSAVA ISATTTANPA APTSDVKTSA
PDTSTYQFDE SSGYYYDPQT GLYYDPNTHY YYNSYTQQYL YWDSEKQAYV PATDCSSTAS
SSSTSAKESK EKKEKPKSKT AQQIAKDMER WAKSLNKQKE NFRSSFQPIS QEERKEAAAA
DAGFTLFEKK QAGGLERLVS EAVKTAEEES SSSKVGLVAA YSGDSEPEET PEGEEKEDKL
TDWKKMACLL CRRQFPSKEA LIRHQQLSDL HKQNLEVHRR SKLSEAELEE LERKETEMKY
RDRAAERREK YGIPEPPAPK KRKFTQPAPV VNYEQPTKDG LNSDNIGNKM LQAMGWKEGK
GLGRNQQGIT APIEAQMRTK GAGLGTKGSN YTLSASDTYK DAVRKAMFAR FTEIE
//
