ID A0A2D0S1U9_ICTPU Unreviewed; 252 AA.
AC A0A2D0S1U9;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Apolipoprotein Ea {ECO:0000313|RefSeq:XP_017336724.1, ECO:0000313|RefSeq:XP_017336725.1};
GN Name=apoea {ECO:0000313|RefSeq:XP_017336724.1,
GN ECO:0000313|RefSeq:XP_017336725.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017336724.1};
RN [1] {ECO:0000313|RefSeq:XP_017336724.1, ECO:0000313|RefSeq:XP_017336725.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017336724.1,
RC ECO:0000313|RefSeq:XP_017336725.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space
CC {ECO:0000256|ARBA:ARBA00004239}.
CC -!- SIMILARITY: Belongs to the apolipoprotein A1/A4/E family.
CC {ECO:0000256|ARBA:ARBA00008788}.
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DR RefSeq; XP_017336724.1; XM_017481235.3.
DR RefSeq; XP_017336725.1; XM_017481236.2.
DR STRING; 7998.ENSIPUP00000014858; -.
DR Ensembl; ENSIPUT00000015482; ENSIPUP00000014858; ENSIPUG00000010115.
DR GeneID; 108272669; -.
DR KEGG; ipu:108272669; -.
DR CTD; 553587; -.
DR OMA; GCQGRFL; -.
DR OrthoDB; 4591103at2759; -.
DR Proteomes; UP000221080; Chromosome 12.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0006869; P:lipid transport; IEA:InterPro.
DR GO; GO:0042157; P:lipoprotein metabolic process; IEA:InterPro.
DR Gene3D; 1.20.120.20; Apolipoprotein; 1.
DR InterPro; IPR000074; ApoA_E.
DR PANTHER; PTHR18976; APOLIPOPROTEIN; 1.
DR PANTHER; PTHR18976:SF2; APOLIPOPROTEIN E; 1.
DR Pfam; PF01442; Apolipoprotein; 1.
DR SUPFAM; SSF47162; Apolipoprotein; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..252
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013510513"
FT COILED 94..228
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 252 AA; 29798 MW; F87F6C148E483811 CRC64;
MKLVAVILAL SVISGCQGSF MFQDEPKTHW EEMVDKFWEY VNGVSSRAED MKNSIQATQL
GRELDTLISD SMAELQMYTD DVKLKLAPYA EQMAQRVQDD LQLLSNKLRV HMEEAKVQIT
AYSQELQTIV EQNRDELQNK VNAYIRKLKK RLNKDTQEIK KKAETYLEEV QARAAQHADD
VNERLKSYFD VVRQNAEDKF NTLKDLLNDQ SQQMMEKWEK LKEQAEQFKM NLYTPFQKKM
EEVKNWFQQF FN
//
