ID A0A2D0S3E5_ICTPU Unreviewed; 287 AA.
AC A0A2D0S3E5;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=heme oxygenase (biliverdin-producing) {ECO:0000256|ARBA:ARBA00012360};
DE EC=1.14.14.18 {ECO:0000256|ARBA:ARBA00012360};
GN Name=LOC108272926 {ECO:0000313|RefSeq:XP_017337279.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017337279.1};
RN [1] {ECO:0000313|RefSeq:XP_017337279.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017337279.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the heme oxygenase family.
CC {ECO:0000256|ARBA:ARBA00006134}.
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DR RefSeq; XP_017337279.1; XM_017481790.3.
DR AlphaFoldDB; A0A2D0S3E5; -.
DR STRING; 7998.ENSIPUP00000024758; -.
DR Ensembl; ENSIPUT00000025790; ENSIPUP00000024758; ENSIPUG00000016750.
DR GeneID; 108272926; -.
DR KEGG; ipu:108272926; -.
DR OrthoDB; 4114903at2759; -.
DR Proteomes; UP000221080; Chromosome 12.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004392; F:heme oxygenase (decyclizing) activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006788; P:heme oxidation; IEA:InterPro.
DR CDD; cd19165; HemeO; 1.
DR Gene3D; 1.20.910.10; Heme oxygenase-like; 1.
DR InterPro; IPR002051; Haem_Oase.
DR InterPro; IPR016053; Haem_Oase-like.
DR InterPro; IPR016084; Haem_Oase-like_multi-hlx.
DR InterPro; IPR018207; Haem_oxygenase_CS.
DR PANTHER; PTHR10720; HEME OXYGENASE; 1.
DR PANTHER; PTHR10720:SF1; HEME OXYGENASE 1; 1.
DR Pfam; PF01126; Heme_oxygenase; 1.
DR PRINTS; PR00088; HAEMOXYGNASE.
DR SUPFAM; SSF48613; Heme oxygenase-like; 1.
DR PROSITE; PS00593; HEME_OXYGENASE; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 267..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 237..261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 287 AA; 32863 MW; B63023AB58161C86 CRC64;
MQVVKQKVQT EKAQITDCDL SEKIKTVTKE SHVRANNTEL MQAFQRGNIT LIQYKLLLCS
LYKIYEALEE ELDRNASHDS VAPIYFPQEL ARTETLMKDL EHFYGQDWRE KMFVPASTLR
YTQRLREIGS EYPEYLVAHA YTRYLGDLSG GQVLSRVPQR SLGLKNGEGL AFFMFPAVSS
PNLFKQLYRS RMNSIELTET QREGVLEEAV RAFELNIQVF DELQNLVNIS EKNELRQRHK
EHNLKTPDVR VSQSSAPSSS LSSPSQLLRM LLGVCLALAV GIGMYAF
//
