ID A0A2D0S4F7_ICTPU Unreviewed; 815 AA.
AC A0A2D0S4F7;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Axin-2 isoform X1 {ECO:0000313|RefSeq:XP_017337644.1};
GN Name=LOC108273124 {ECO:0000313|RefSeq:XP_017337644.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017337644.1};
RN [1] {ECO:0000313|RefSeq:XP_017337644.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017337644.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR RefSeq; XP_017337644.1; XM_017482155.3.
DR RefSeq; XP_017337645.1; XM_017482156.1.
DR AlphaFoldDB; A0A2D0S4F7; -.
DR STRING; 7998.ENSIPUP00000022444; -.
DR Ensembl; ENSIPUT00000023392; ENSIPUP00000022428; ENSIPUG00000015211.
DR Ensembl; ENSIPUT00000023409; ENSIPUP00000022444; ENSIPUG00000015211.
DR GeneID; 108273124; -.
DR KEGG; ipu:108273124; -.
DR OMA; CVHEEVG; -.
DR OrthoDB; 4256282at2759; -.
DR Proteomes; UP000221080; Chromosome 12.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:InterPro.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 1.10.196.10; -; 1.
DR Gene3D; 2.40.240.130; -; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR043581; Axin-like.
DR InterPro; IPR014936; Axin_b-cat-bd.
DR InterPro; IPR032101; Axin_TNKS-bd.
DR InterPro; IPR001158; DIX.
DR InterPro; IPR038207; DIX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR024066; RGS_subdom1/3.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR46102; AXIN; 1.
DR PANTHER; PTHR46102:SF1; AXIN-2; 1.
DR Pfam; PF16646; AXIN1_TNKS_BD; 1.
DR Pfam; PF08833; Axin_b-cat_bind; 1.
DR Pfam; PF00778; DIX; 1.
DR Pfam; PF00615; RGS; 1.
DR PRINTS; PR01301; RGSPROTEIN.
DR SMART; SM00021; DAX; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50841; DIX; 1.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW ADP-ribosylation {ECO:0000256|ARBA:ARBA00022765};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687}.
SQ SEQUENCE 815 AA; 90368 MW; FC19813E93A94C00 CRC64;
MSRALIEPVT TSFREDAPRP PVPGEEGEEE ASSSLSRCDP SAYMKIKNAV KSARAPRRDE
DGLGEPEGSA SPDSPLARWT KSLRSLLADQ DGAHLFRTFL ERERCEDALD FWFACNGFRQ
MDLQDAKTRR VARAIYKRYV EGRGVVAEHL RAATRACIRE SVKKQRIELR MFDQAQTEIE
GGLEESAYRA FLTSDIYLDY VRSGGENAAC AGHAHAHGGL ASLELVCGYL PPLIEDKEWS
CGELKAKALA AVVGLSAETL RATMTLRTAD CRAQKRGDPA SPYFVNSGHV VAPASSANDS
EVSSDATTDD SMSMTDSSVD GIPPYKLGTK KQLQREMHRS VKINGQVSLP HFPRTQRLPR
EMAPVKPSAF AAELIARLEK LKREQDTLSS LEERLQQIQE EEERDDSELP VVVPQPPPAA
LSLLSSGLCD EDPQAILDEH LSRVLKTPGC QSPGIPGYSP RSRSPDHHHQ QGSTPNLLPS
MHCSVPSKTP GMAPQPSTKH IHHHYIHHHH SASPKSREEM EAEAAHRVAQ CLGSSGSDYC
YQRCHNSADL QQGRTSTLSK RPSNISDGMS GCKSSEEESS SPLLPRDGIV RSHNVWQWIL
ESERQNRHKP HGSQGLKKVH PSDLSSKTPL WGGGGVGGHA RAHHPGHPFV QDPTMPPLSP
PNTLTQLEEA CRRLEEASKP TKQRHSASSL QKERVHPSLF SNSSSPLISP ALQMDEWKEQ
RRLSAGHSSA HSGSELVVTY FFCGEEIPYR RLMKTHSLTL GHFKEQLRKK GNYRYYFKKA
SDEFECGAVF EEIWEDGTVL PMYEGKILGK VERMD
//
