ID A0A2D0S755_ICTPU Unreviewed; 611 AA.
AC A0A2D0S755;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=T-box transcription factor TBX21 {ECO:0000313|RefSeq:XP_017338579.1};
GN Name=tbx21 {ECO:0000313|RefSeq:XP_017338579.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017338579.1};
RN [1] {ECO:0000313|RefSeq:XP_017338579.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017338579.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
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DR RefSeq; XP_017338579.1; XM_017483090.3.
DR AlphaFoldDB; A0A2D0S755; -.
DR STRING; 7998.ENSIPUP00000027284; -.
DR Ensembl; ENSIPUT00000028406; ENSIPUP00000027293; ENSIPUG00000018470.
DR GeneID; 108273685; -.
DR KEGG; ipu:108273685; -.
DR CTD; 30009; -.
DR OrthoDB; 5323209at2759; -.
DR Proteomes; UP000221080; Chromosome 13.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0009790; P:embryo development; IEA:UniProt.
DR GO; GO:0060429; P:epithelium development; IEA:UniProt.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd20203; T-box_TBX21; 1.
DR Gene3D; 2.60.40.820; Transcription factor, T-box; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR032385; T-box_assoc.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR PANTHER; PTHR11267:SF125; T-BOX TRANSCRIPTION FACTOR TBX21; 1.
DR Pfam; PF00907; T-box; 1.
DR Pfam; PF16176; T-box_assoc; 1.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS01283; TBOX_1; 1.
DR PROSITE; PS01264; TBOX_2; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00201};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00201}; Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 159..344
FT /note="T-box"
FT /evidence="ECO:0000259|PROSITE:PS50252"
FT REGION 569..611
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 611 AA; 67530 MW; 01ABC00CBDFF1561 CRC64;
MGGIGGSFYI NMLNGSDAQS LAKDAETSGH LHRSKELADF KMGVQDARLY YPDSVPNGQD
NFPLPYHGEQ SAGELGAQAG RLYSAAAAAA AAAPLGNCAF TRSSAAQAYA AADGYSPDCK
DGHSASADSY HAHFQHGYPR APLYSLPGLQ VCGKTQVLLN NYPLWAKFHK YQTEMIITKQ
GRRMFPFLSF NISALDPSAH YNVYVDVVLA DQHHWRYQGG KWVQCGKAEG NMPGNRMYMH
PDSPNTGNHW MRQEVSFGKL KLTNNKGGSN NMSQMIVLQS LHKYQPRLHI MEVKEDGTED
PFRSCKAQTF IFPETQFIAV TAYQNADITQ LKIDHNPFAK GFRDNYDTLY APPDSDRITP
SPTEGQQLMA ASCYPRQPYL AEQYMSPLQH SRFYSCEPVS MAQACPKDPS GSHHGRWYLP
GQQGTPSNLL DFTSYDGDYT ANSLYKPFTL QTSPHHPLSY YPEIPFTSGP ISSASPATWS
TARPSPQYLS HSHPGKASSS LSWFRPMSSP AMSSSPPAIN PRLHNSPSIL ESLRLPVLQD
KPKEVVEDTW METPSVKSVD SVDSGLFEGA ESKKRRVSPY ASSTENSPPI RSEACEKDNS
SDAGYYGFYS H
//
