ID A0A2D0S859_ICTPU Unreviewed; 1294 AA.
AC A0A2D0S859;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=C-Jun-amino-terminal kinase-interacting protein 4 isoform X3 {ECO:0000313|RefSeq:XP_017338929.1};
GN Name=spag9b {ECO:0000313|RefSeq:XP_017338929.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017338929.1};
RN [1] {ECO:0000313|RefSeq:XP_017338929.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017338929.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the JIP scaffold family.
CC {ECO:0000256|ARBA:ARBA00009866}.
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DR RefSeq; XP_017338929.1; XM_017483440.3.
DR STRING; 7998.ENSIPUP00000008624; -.
DR GeneID; 108273832; -.
DR KEGG; ipu:108273832; -.
DR CTD; 100333761; -.
DR OrthoDB; 3685563at2759; -.
DR Proteomes; UP000221080; Chromosome 13.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0005078; F:MAP-kinase scaffold activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.20.58.1770; -; 1.
DR Gene3D; 1.20.5.1000; arf6 gtpase in complex with a specific effector, jip4; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR039911; JIP3/JIP4.
DR InterPro; IPR032486; JIP_LZII.
DR InterPro; IPR019143; JNK/Rab-associated_protein-1_N.
DR InterPro; IPR034743; RH1.
DR InterPro; IPR034744; RH2.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR13886:SF2; C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 4; 1.
DR PANTHER; PTHR13886; JNK/SAPK-ASSOCIATED PROTEIN; 1.
DR Pfam; PF16471; JIP_LZII; 1.
DR Pfam; PF09744; Jnk-SapK_ap_N; 1.
DR Pfam; PF19056; WD40_2; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS51776; RH1; 1.
DR PROSITE; PS51777; RH2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Kinase {ECO:0000313|RefSeq:XP_017338929.1};
KW Transferase {ECO:0000313|RefSeq:XP_017338929.1}.
FT DOMAIN 6..94
FT /note="RH1"
FT /evidence="ECO:0000259|PROSITE:PS51776"
FT DOMAIN 483..554
FT /note="RH2"
FT /evidence="ECO:0000259|PROSITE:PS51777"
FT REGION 209..303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 792..822
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 864..890
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1217..1237
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 60..161
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 428..511
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 713..740
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 227..242
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 256..298
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 804..822
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 874..888
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1294 AA; 143305 MW; BA48B8515F537899 CRC64;
MELEDGVLYQ EDSGSSSMMS ERVSGLASSI YREFERLIRK YDEDVVKELM PLVVAVLENL
DSVFAENQEH EVELELLKED NEQLVTQYER EKALRKGVEE RYMEIEDLQD QERKELQSKV
TTLEGLTRQL ELKTKNYADQ IGRVEEREAE LKKEYNALHH RHTEMIHSYM EHLERTKMQQ
LAGGEPTDTS TMSRHRKERP VSLGIFQLQG DVRTPELQRE QAATPGTDAW RFNNLSHPHS
NTSLKDELSD ANRGGSKSAL PMSTAPSDAA SASVAVSQAE ESEGLNRNLN SSSRKPDSSK
NIKVQEAVAT EVLPKDVLEN TEKSEVQAII ESTPELDMDL SGCKGSSTPA KGIENMAFDR
NTDSLFEELS SAGTDLIGDV DEGADLLGMG REVEHLIQEN AQLLETKNTL NIVKNDLLGR
VDQLTCDKEV LHGEMEVLKQ AKDKLEEKNK ELEEEIKRVR AELEVAKQKT KEEDDSDVPT
AQRKRFTRVE MARVLMERNQ YKERLMELQE AVRWTEMIRA SRENPTLTEK KKSSIWQFFS
RLFSSSSSSA AKKPEAPVNV KYNAPTSHIV PSVKKRSSTL AQLPSDKSKA FDFLNDDPEV
ENIVSRREQK RAQYQQVKAH VQKEDGRIQA CGWSLPQKYK VSNAQADSKV KNLPVPVYLR
PLDEKDASMK LWCAAGVNLS GGKTRDGGSI VGASVFYRDV SAPESGGLSP RLARGSRSSL
DKLEQELKEQ EKELRQQDEL SSLVWICTST HTTSKVIVID ANQPGKILES FFVCNSHLLC
ITSVPGARET DYPAGEEVSA NSQAGGAEGA SHTGTAANSS VAGSERVLDG ITVVGCSVEG
AVAVSQTAGT DSVDADVLEQ RRQPGVAAAE EALEATESSN TTPAEESQPG IYTEHVFTDP
LGVQNNRDPL SSYTQRECDL VKDGVSLIPE EQDLMREEAN KMSSVLPTMW LGAQNGCIYV
HSSVAQWKKC LHSIKLKDSI LGIVHVKGRV LVALADGTLA IFHRGVDGQW DLTNYHLLDL
GRPHHSIRCM TVVHDKVWCG YRNKIYVIQP KAMKIEKSFD AHPRKESQVR QLAWDGDGIW
VSIRLDSTLR LFHAHTFQHL QDVDIEPYVS KMLGTGKLGF SFVRITALMV SCNRLWVGTG
NGVIISIPLT ETKTVTQGTS NRPGSVIRVY GDENSDKVTA GTFVPFCSMA HAQLCFHGHR
DAVKFFTAVP GHVVPSAGAG GEAGGDKPTA DSPTPEFSKS VLVMSGGEGY IDFRMGDEGG
EGEDLSEPAL KLQPFLAKAE RSHLIVWQVM VNGD
//
