ID A0A2D0SEJ9_ICTPU Unreviewed; 678 AA.
AC A0A2D0SEJ9;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Eomesodermin homolog a {ECO:0000313|RefSeq:XP_017340670.1};
GN Name=eomesa {ECO:0000313|RefSeq:XP_017340670.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017340670.1};
RN [1] {ECO:0000313|RefSeq:XP_017340670.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017340670.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
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DR RefSeq; XP_017340670.1; XM_017485181.3.
DR AlphaFoldDB; A0A2D0SEJ9; -.
DR STRING; 7998.ENSIPUP00000005675; -.
DR Ensembl; ENSIPUT00000005935; ENSIPUP00000005675; ENSIPUG00000003957.
DR GeneID; 108274799; -.
DR KEGG; ipu:108274799; -.
DR CTD; 64603; -.
DR OMA; GPACLYP; -.
DR OrthoDB; 5323209at2759; -.
DR Proteomes; UP000221080; Chromosome 14.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0042074; P:cell migration involved in gastrulation; IEA:Ensembl.
DR GO; GO:0048263; P:determination of dorsal identity; IEA:Ensembl.
DR GO; GO:0001714; P:endodermal cell fate specification; IEA:Ensembl.
DR GO; GO:0090504; P:epiboly; IEA:Ensembl.
DR GO; GO:0055109; P:invagination involved in gastrulation with mouth forming second; IEA:Ensembl.
DR GO; GO:0048382; P:mesendoderm development; IEA:Ensembl.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 2.60.40.820; Transcription factor, T-box; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR032385; T-box_assoc.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267:SF13; EOMESODERMIN HOMOLOG; 1.
DR PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR Pfam; PF00907; T-box; 1.
DR Pfam; PF16176; T-box_assoc; 1.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS01283; TBOX_1; 1.
DR PROSITE; PS01264; TBOX_2; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00201};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00201}; Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 236..421
FT /note="T-box"
FT /evidence="ECO:0000259|PROSITE:PS50252"
FT REGION 1..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 174..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 426..445
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 481..500
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 643..663
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..51
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 52..66
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..94
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 177..195
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 429..445
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 484..500
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 678 AA; 73603 MW; BDC78949DC9187E9 CRC64;
MQLESLLPSL PKTFYTLSSS SSSSSSSSDS TSPGSTHANT HASTHTNSAH SFGEAERPEH
ELQPGKKYRS AMMMSSSSST SGSTGTTTAT GGEREGDEFS TGSKSRKSSP VIGGGAEEDE
ELVTRRYGIE ELGTDRYFIS PSSDASACSL FPYGAQGGSV YGGAGARYSS PYSSAASVLA
PPPPPPPPPP PPGAVCSSRA QLAPPPAAAY QFGQGPACLY PSYHPGLAVG RAQVYLCNRA
LWLKFHRHQT EMIITKQGRR MFPFLSFNIA GLNVSAHYNV FVEVVLADPN HWRFQGGKWV
TCGKADNNMQ GNKMYVHPES PNTGAHWMRQ EISFSKLKLT NNKGANNNNT QMIVLQSLHK
YQPRLHIVEV SEDGVEDMGG ESKTQTFTFP ENQFIAVTAY QNTDITQLKI DHNPFAKGFR
DNYDSMYTAP ESDRLTPSPT DSPRSHQIVP GARYAMQPFF QDQFVNNLPQ NHRLYGGERA
VPQTNGLLSP QSDDSSISAT SSSSAAQRWF VTPVQQNEAD YSVLPYGIKP LPLQSPHSFG
YYPESSAFAS ISAGWSSGRS SYQRKMAAGL PWSPRPSPPS FSFPEDPLTT TTITTSIKDK
LQDEGTPVTA GAGGVWGLET ASNLKPLDKF DAPYAMVCKR RRLSSGTDAS PTIKCEDVTS
DDYGKEQPKS YYAFYTSP
//
