ID A0A2D0SKW5_ICTPU Unreviewed; 572 AA.
AC A0A2D0SKW5;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN Name=trim101 {ECO:0000313|RefSeq:XP_017343126.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017343126.1};
RN [1] {ECO:0000313|RefSeq:XP_017343126.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017343126.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
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DR RefSeq; XP_017343126.1; XM_017487637.3.
DR AlphaFoldDB; A0A2D0SKW5; -.
DR STRING; 7998.ENSIPUP00000017228; -.
DR Ensembl; ENSIPUT00000017959; ENSIPUP00000017228; ENSIPUG00000011699.
DR GeneID; 108276180; -.
DR KEGG; ipu:108276180; -.
DR CTD; 445187; -.
DR OrthoDB; 5383069at2759; -.
DR Proteomes; UP000221080; Chromosome 15.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR003649; Bbox_C.
DR InterPro; IPR017903; COS_domain.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF602; ZGC:101050; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR SMART; SM00502; BBC; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51262; COS; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
SQ SEQUENCE 572 AA; 64588 MW; BDFF56D54090A7DA CRC64;
MSLPLDLSSF HKDASLGTLE KQLICPICLE VFTKPVVILP CQHNLCRKCA NELYQPSLFQ
VGIGGRFRCP SCRHEVVLDR HGVYGLQRNL LVENIIDVYK QASASCRPPP KPLAQMNCEE
HEGEKLNIYC ITCQIPTCSL CKVFGAHKSC QVAPVSDVYQ QQKTELSDGI GSLVATNERI
QACINDLEEI CRSVEENSRN QKQILCEKFD RMSGILEERR KIMLQRITYE EDEKRSWAQS
LVQTYSEQVD INSKLVQSAL NAMEEPEMAA FLQTSKNLIE QVSEATKSAP VETLQPGYET
MDHYKVDFNA EERALYQLDF IKPEEEVEEP PEEPEPEPES EVLPEPEPEP ETEPVYSLVE
NSEPDNELKL ENYEIKDVLS ETKEENQAIV EGGSARRKDV ICEKGGLNTQ QDQTELGCEG
HGSGIHCLTS EAGEETKLYP TWYRPNNWPM LSQSQATPID ALGDLDHIPK LMSEPSGQFQ
QTETPLSMWT GSSLMPLSNE NRAQLVRGTL ESTQPYMLEV EKNICCELVS GPANKDSVTS
ISPQAIIHIF YVLAFLVILQ RVWGNIRCFF FI
//
