ID   A0A2D0SLG8_ICTPU        Unreviewed;       578 AA.
AC   A0A2D0SLG8;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=Protein NDNF {ECO:0000256|ARBA:ARBA00024096};
GN   Name=ndnf {ECO:0000313|RefSeq:XP_017343547.1};
OS   Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC   Ictaluridae; Ictalurus.
OX   NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017343547.1};
RN   [1] {ECO:0000313|RefSeq:XP_017343547.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_017343547.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR   RefSeq; XP_017343547.1; XM_017488058.3.
DR   AlphaFoldDB; A0A2D0SLG8; -.
DR   STRING; 7998.ENSIPUP00000001726; -.
DR   Ensembl; ENSIPUT00000001803; ENSIPUP00000001721; ENSIPUG00000001233.
DR   GeneID; 108276412; -.
DR   KEGG; ipu:108276412; -.
DR   CTD; 79625; -.
DR   OMA; KFCIYRK; -.
DR   OrthoDB; 2876995at2759; -.
DR   Proteomes; UP000221080; Chromosome 15.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR019326; NDNF.
DR   InterPro; IPR045805; NDNF_C.
DR   PANTHER; PTHR14619; NEURON-DERIVED NEUROTROPHIC FACTOR; 1.
DR   PANTHER; PTHR14619:SF1; PROTEIN NDNF; 1.
DR   Pfam; PF10179; NDNF; 1.
DR   Pfam; PF19433; NDNF_C; 1.
DR   SMART; SM00060; FN3; 2.
DR   SUPFAM; SSF49265; Fibronectin type III; 2.
PE   4: Predicted;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..578
FT                   /note="Protein NDNF"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012497334"
FT   DOMAIN          176..333
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|SMART:SM00060"
FT   DOMAIN          455..564
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|SMART:SM00060"
FT   REGION          99..121
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          274..293
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   578 AA;  64696 MW;  A2538AE7DBBB66E4 CRC64;
     MRRVIGCFAV LLLSSTLAVF GQKLPTRDEG LFQMQIRDKA LFHDSSVIPD GAEISGYLFR
     DTPKRYYFVV EEDNTPLSVT VTPCDAPLEW RLTLQELPEE ASGDGSGEPE PLEQQKQQVT
     ANEGTELFSY KGNDVESFVS SSSPSGLYQL DILSTEKDSS LKIYATTTPE SDQPYPELPY
     DPRVDVTSLG RTTVTLAWKP TPTGSRMGQP VHYCVVVNKE HNFKSLCAAE AKMGADDSFM
     VAPKPGLDFS PFDFARFGFT SPENDLTKDR HRSLSANRVP ASKPWRSPGT NPRPSDIRKI
     CIGNKNIFTV SGLRPATQYY FDVFAVNVAS NASTAYVGTF ARTKDEAEPK TVELKDGKMA
     DIFVERKGIK LLRFAPVSSH RRVSLSVHSC LDAVHVQVRR DGKLMLSQNV EGVREFQLRA
     KPKAKYLIRV RGSRKGASAL KVLASTRADT KRPFPSLPED TRIKAFDRLR TCESVTVAWL
     GTQERNKYCV YQREVPDGYG EEQRRRQRNQ CAGPETRRRD EKVLCKHFHS ANPHKAVTTE
     TITGLEPGKS YVLDVYAIGH GGHSVKYQSK LVKTRKYC
//