ID A0A2D0SMD5_ICTPU Unreviewed; 2368 AA.
AC A0A2D0SMD5;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2023, sequence version 2.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Chondroitin sulfate proteoglycan 4 {ECO:0000313|RefSeq:XP_017343868.2};
GN Name=LOC108276592 {ECO:0000313|RefSeq:XP_017343868.2};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017343868.2};
RN [1] {ECO:0000313|RefSeq:XP_017343868.2}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017343868.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00122}.
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DR RefSeq; XP_017343868.2; XM_017488379.3.
DR STRING; 7998.ENSIPUP00000032382; -.
DR Ensembl; ENSIPUT00000033664; ENSIPUP00000032382; ENSIPUG00000021772.
DR KEGG; ipu:108276592; -.
DR OrthoDB; 4072625at2759; -.
DR Proteomes; UP000221080; Chromosome 16.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00110; LamG; 2.
DR Gene3D; 2.60.120.200; -; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR039005; CSPG_rpt.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR45739:SF12; CHONDROITIN SULFATE PROTEOGLYCAN 4-LIKE ISOFORM X2; 1.
DR PANTHER; PTHR45739; MATRIX PROTEIN, PUTATIVE-RELATED; 1.
DR Pfam; PF16184; Cadherin_3; 12.
DR Pfam; PF02210; Laminin_G_2; 2.
DR SMART; SM00282; LamG; 2.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 2.
DR PROSITE; PS51854; CSPG; 11.
DR PROSITE; PS50025; LAM_G_DOMAIN; 2.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 2238..2261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 6..183
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 193..371
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REPEAT 400..495
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 527..620
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 868..957
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1087..1177
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1199..1295
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1311..1404
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1428..1518
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1535..1636
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1661..1760
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1794..1886
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1903..1991
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REGION 2173..2229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2345..2368
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2186..2219
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2348..2368
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2368 AA; 264610 MW; DD0B797B345C1258 CRC64;
MINRTESGAS FYGDGFVRLK TVESSSKNTL HVRFRTSSGD GLLFLAAGET DFLWVALQAG
RIQVQVELGS GERTLRSEKA APLNDLTWHA IELQHNGQNI TLTVDKSSWS SLRMPGPDLE
LSVQDGLYVG GLENSDKLYL FNDISHMGFR GCLDEVLFNE HNLLSSLRPY SGYKMVHEVS
LGCSPQFSAS VNDSISFFSS KAYMSLPMWE VPQEGVFECE FYTSAEDGLL LYSSAGKGDY
VALEIRHKRL VAVVRVDGSK TALSSITVVS EGWHSVRLYV APRALQLTVG EEILNSSFGA
KSRALQLNGP LFLGGVDANT FSEVRRNGLL SVVSKHLSGG SFKGCLRNIR VNDQNMGLPN
AVVTKDVSVG CEPVKHVKPI TTTNPETLQP ETPQLDKTDS QTFLILKDLE VPEGGRAPLE
SKHIKLNLDF RKLGIRQSQI MFRIEEQPVH GQLRLDVDPD QLENAFSILA LWHGQVMYVH
GGSEDPQDFF MFSVFTTSTN KEVPGYLKGS HLHRFNITVT PINDAPELSL PEGNLFILLE
NSKRHLSMDM LRATDPDSNY TELVFSLLGN LIANAGFLEL ADNPGKPVTS FSYSDLEGGK
VSFVHKGIKN SRMAIRVSDG EKVSNTVVLR IMAVTLEYKV VNNSGVDVIQ GRSSHIGSKH
LAVQVNVAKQ VMDIRYDVLD PPFYGELQRL HSSGEWKQTG TFTQKLLEKD RLRYLSTFHG
PQFKNVTDGF KCKISVGSAS TGEVLVRVRV RWIQYKVTRS KMEVKDDRKV TLTPQEFRIV
SKNVKLSEND LHVCLLTLPR RGVLLFNDKP LKKNSTFSQR NITDQKVQYK LFEKPNKNLR
DMFSFQVFSE YSYSGRHDFR ISIKPNVPSV VLRNHGLSLL EGESKIITKD NLFFETFGSG
AVRYTVVSSP QHGKLLRINN SRHNIAEFTN QDILEERVLY VHDDSETTRD AFTFWASASS
PNDVEGVFNI SIQLVNDQKP VRVVDKVFHV ARDSQRLLTS EDLRYHDPDS DYDDGQLLYT
RRGISVGELV SVNDTSHKLY RFHQRDLEEK RVLFVHSGAN FGRFVLFVSD GKHYTSTLLE
VSAQEPYLKV ANNTGLLVQK GQEVMLQSVN FSVTTNTDVR SDEDVLFEIF HPPSHGVLLC
EGVEADAFTQ YDLKAGHLVY RHDDGRNLMD SFSLTATVNR LRLDVTVPVK VYLESHQKPP
QVIHNHSVVV EEGKHVQIHK TQLEVVHEDN TPDEIMYTMR TPPSHGFLMR SRVDGQDRHD
GTVETFSQWD INAGHIRYVQ EKHGRTDDSF SLDVTNGIGT VSDLVVFVEI VPSFLPLEVS
NITLKEGSST ALTEDVIKVT GRHFTELHVQ YHVIDGPRHG RIEHSRIPGV PIPSFTRVQV
EHAFISYVHD GSETIGDNFT LVANDTDVRK QSEPRVIHVT VTPVNDEAPV ITINRILRVW
VDSVTEITSD DLSASDLDSA PENLEFIITP PSNGHLALKS APSRPVLNFT QAHIHRRQLV
FLHRGALFGG FHFQVNDGVN FAPRQIFSIA ARSLELSLER NRELKVFPGS SKVISVEDLF
IATNDYDDIH ENRTVVYSVT SPPRLGRLIR PQDDSSTETK PISTFTQNML KAGLVVYEHT
EPISWTATDY FIFTASSPPA SFPPHTFNIR ISYDNTSPEH GSVLLANTGA VVVEGSRIMI
DKSKLDASNL LGKLPEEERD SYEIWYRVTT LPRFGTIVVG ERNLTREKPV FPQLILNKYG
ISYVHDDSET ICDSFSFDVW LNPIGRPAQQ PQEEDFMVSE SFNITVTPVN DLPPLLKTQA
PSLLVVKGDT VALGPENLHV EDLDTLPEDI HYTVISKPNN GFLALEGRLN ESTVTFTQAD
VNEGRVHFVQ EGRPTSGIFY FSVTDGFHRP LYKLFNLEVH NVTVDVVNNT GLTLVQGRTT
GSLTLQHLAA VTNKKNATIK YYITTPPSHG RLVIKEDQIT HFDQEELRLG RVLYQMADLS
SSQDSFEFTV VASESNLTNQ VFNITVKPLI HLGKQVRIPD GIPVKIRKDV LDATELASIS
GSDPIFEIII PPKYGKLVKV TVNLGGASES IESFTFRDVE QGRIAIQEHL NFLAVYGNTT
AVVHNKTAPA LEDSFVFLLK AANVQPARGE FVFMVVPYDP MTGKHVVSAA PVYPTVHPAF
NRTSNVVSHV NRPAHMHPTK TPHWVPPKTK TRNRSGNHTR GKATVSNAPK TTSGRHNDPP
RNTPIRVESL PRPASDPLLI ILPFLACLFL IIILVVLILV FRHRQEKRAQ PSMLQDLPEN
SVEDIVSPSP YLGQPERSLT VPSVVVTPLL PRCPRSPVLE AVHNGAVVPA IVLPDSSMLV
CPWTPMDPDG TPQSSPGSPT LRQNQYWV
//
