ID A0A2D0SME5_ICTPU Unreviewed; 757 AA.
AC A0A2D0SME5;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2023, sequence version 2.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Kin of IRRE-like protein 3 {ECO:0000313|RefSeq:XP_017343878.2};
GN Name=kirrel3a {ECO:0000313|RefSeq:XP_017343878.2};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017343878.2};
RN [1] {ECO:0000313|RefSeq:XP_017343878.2}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017343878.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR RefSeq; XP_017343878.2; XM_017488389.3.
DR AlphaFoldDB; A0A2D0SME5; -.
DR STRING; 7998.ENSIPUP00000030274; -.
DR KEGG; ipu:108276601; -.
DR OrthoDB; 5362512at2759; -.
DR Proteomes; UP000221080; Chromosome 16.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR CDD; cd05759; IgI_2_KIRREL3-like; 1.
DR CDD; cd05898; IgI_5_KIRREL3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR11640:SF49; KIN OF IRRE-LIKE PROTEIN 3; 1.
DR PANTHER; PTHR11640; NEPHRIN; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..757
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013510464"
FT TRANSMEM 496..522
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..116
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 121..217
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 224..304
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 309..389
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 394..489
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 724..757
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 724..749
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 757 AA; 82179 MW; B0C10957D6DB82EB CRC64;
MFSLFSSILL LVLLLSGFGS CAVFIQQPHD VVVVAGQPVT LPCAITGYHG MVLWVKDGLA
LGVNRDMSGY PRYDVVGDHS KGEYHLLIQR TELADDGSFE CQGIQAGIRS RPARLTVLVP
PEDPVIIGAP VVSLRAGDPL NLTCHADNAK PAASIIWIRN GEVLNGAMYS KTLLRDGHRE
STVSTLYVSA SNIESGQRIT CRASNKAAPN GKEATVTIDI QHLPLVNLSA EPQPILEGNP
VRFHCSAKAN PPVTQYRWAK GGTVIRDAVG ETYEVAVDHS FFTEPVSCEV TNALGSTNIS
RNVDVYFGPR LAAEPQSLQV DLGSDAVFNC AWMGNPSLTI VWMKRGHGVV LSNENTLTLR
AVKQEDAGKY VCRAVVPRVG VGEKVVTLTV NGPPTISSTQ TQQALYGEKG QIKCFIRSTP
PPDRIAWSWK ETVLESGTSG RYTVETVSTE EGVISTLTMS NIVPADFQTI YNCTAWNSFG
SDTEIIRLKE HGSLRLAVII GVAVGAFLAL IVLMGTLGAF CCARLQRKDM HLVMSSLPVS
LSARQRELSS AIKTESLKGV VSAKNDIRVE IVHKDHNAAR ETEEHAGAKQ MMMERGEFQQ
ESVLKQLEVL QEEEEEFQHV KDPTNGYYSV NTFKEHNATT SAEVRNPSGS ATLGKQRVPT
GMSFTNIYST LGAAPNHRLY DYGGRFVLAM GSSSIELCER ELSDSGSFQD APCDSSASSY
FDKASKASAS SSTHHSQSSS QNSDLTRPLQ KRMLTHV
//
