ID A0A2D0SPD5_ICTPU Unreviewed; 202 AA.
AC A0A2D0SPD5;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=High mobility group protein B1a {ECO:0000313|RefSeq:XP_017344145.1};
GN Name=hmgb1a {ECO:0000313|RefSeq:XP_017344145.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017344145.1};
RN [1] {ECO:0000313|RefSeq:XP_017344145.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017344145.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC -!- SIMILARITY: Belongs to the HMGB family.
CC {ECO:0000256|ARBA:ARBA00008774}.
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DR RefSeq; XP_017344145.1; XM_017488656.3.
DR AlphaFoldDB; A0A2D0SPD5; -.
DR STRING; 7998.ENSIPUP00000028049; -.
DR Ensembl; ENSIPUT00000029190; ENSIPUP00000028049; ENSIPUG00000018990.
DR GeneID; 100304841; -.
DR KEGG; ipu:100304841; -.
DR CTD; 321622; -.
DR OMA; LYSEYRP; -.
DR OrthoDB; 1222485at2759; -.
DR Proteomes; UP000221080; Chromosome 16.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0003690; F:double-stranded DNA binding; IEA:UniProt.
DR GO; GO:0031103; P:axon regeneration; IEA:Ensembl.
DR GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR CDD; cd21978; HMG-box_HMGB_rpt1; 1.
DR CDD; cd21979; HMG-box_HMGB_rpt2; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 2.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR InterPro; IPR017967; HMG_boxA_CS.
DR PANTHER; PTHR48112:SF12; HIGH MOBILITY GROUP PROTEIN B1; 1.
DR PANTHER; PTHR48112; HIGH MOBILITY GROUP PROTEIN DSP1; 1.
DR Pfam; PF00505; HMG_box; 1.
DR Pfam; PF09011; HMG_box_2; 1.
DR PRINTS; PR00886; HIGHMOBLTY12.
DR SMART; SM00398; HMG; 2.
DR SUPFAM; SSF47095; HMG-box; 2.
DR PROSITE; PS00353; HMG_BOX_1; 1.
DR PROSITE; PS50118; HMG_BOX_2; 2.
PE 3: Inferred from homology;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00267}.
FT DOMAIN 8..78
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 94..162
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 8..78
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 94..162
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 72..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 164..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 72..93
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 180..202
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 202 AA; 23323 MW; 7D51C46748B8C39E CRC64;
MGKDPAKPRG KMSSYAYFVQ TCREEHKKKH PDTSVNFSEF SKKCSERWKT MSAKEKGKFE
DMARLDKARY EREMKNYVPP RGEKKKRFKD PNAPKRPPSA FFIFCAEYRP KVKEETPGLS
IGDVAKKLGE MWNKTSAEEK QPYEKKAAKL KEKYEKDIAA YRKGKVVGGA AKAPTKPDKA
DEDEDEDDDD EDDDDDDDED DE
//
