ID A0A2D0SSK1_ICTPU Unreviewed; 485 AA.
AC A0A2D0SSK1;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=E3 ubiquitin-protein ligase TRIM50 {ECO:0000313|RefSeq:XP_017345672.1};
GN Name=LOC108277430 {ECO:0000313|RefSeq:XP_017345672.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017345672.1};
RN [1] {ECO:0000313|RefSeq:XP_017345672.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017345672.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_017345672.1; XM_017490183.3.
DR AlphaFoldDB; A0A2D0SSK1; -.
DR STRING; 7998.ENSIPUP00000030363; -.
DR Ensembl; ENSIPUT00000031584; ENSIPUP00000030363; ENSIPUG00000020505.
DR GeneID; 108277430; -.
DR KEGG; ipu:108277430; -.
DR OMA; DVCWHER; -.
DR OrthoDB; 3453019at2759; -.
DR Proteomes; UP000221080; Chromosome 17.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF326; E3 UBIQUITIN-PROTEIN LIGASE TRIM50-RELATED; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 16..57
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 87..128
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 281..480
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
SQ SEQUENCE 485 AA; 54966 MW; AF6A42611A0DE329 CRC64;
MARRSSLESL EEQLRCPVCL EVFSEPLMLQ CGHSYCRGCV RSIDMDPLGQ LQCPVCRCAV
DGDSPPPNVA LARIVDALRE INEPGQGPPE TCNQHHNPLS LYCEEDQTLI CGLCGSIGSH
RAHKVTPISS VYSRMKEDIS CLMTNFQTQK RKLEEQICKM AYNKSRITNE SDVLKWVVRK
EFGELRHCVE LEEASFMQKV ENTASTLIAS IQTQADHMSQ LLAKFQEAEG TLEALSNEGH
LDFITKYGSI APRFRESQQR EQRKERTYSS ISFNPGFNHS DIKMTVWKRL HRRVLPAPEC
LKFDSLTAHP MLQLSEDNTS VQCGVLVNRL PNNPERFSYS YCVLANRGFS SGKHYWEVQV
GEKPKWRLGL IKGTACRKSK LPKSPEGGVW LIGLKEGRLY EAFSTPRVTL PLMSQPHCLG
VFLNYERGEL TFYNADSPDE LGFIYSYQAE LQGKVYPLFD VCWQERGANK LPISLPHPLT
EAYGD
//
