ID A0A2D0SUP5_ICTPU Unreviewed; 607 AA.
AC A0A2D0SUP5;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Autophagy-related protein 16-1 isoform X2 {ECO:0000313|RefSeq:XP_017346035.1};
GN Name=atg16l1 {ECO:0000313|RefSeq:XP_017346035.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017346035.1};
RN [1] {ECO:0000313|RefSeq:XP_017346035.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017346035.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the WD repeat ATG16 family.
CC {ECO:0000256|ARBA:ARBA00009271}.
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DR RefSeq; XP_017346035.1; XM_017490546.3.
DR AlphaFoldDB; A0A2D0SUP5; -.
DR GeneID; 108277711; -.
DR CTD; 55054; -.
DR OrthoDB; 458014at2759; -.
DR Proteomes; UP000221080; Chromosome 17.
DR GO; GO:0000045; P:autophagosome assembly; IEA:InterPro.
DR CDD; cd22887; Atg16_CCD; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR045160; ATG16.
DR InterPro; IPR013923; Autophagy-rel_prot_16_dom.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19878; AUTOPHAGY PROTEIN 16-LIKE; 1.
DR PANTHER; PTHR19878:SF6; AUTOPHAGY-RELATED PROTEIN 16-1; 1.
DR Pfam; PF08614; ATG16; 1.
DR Pfam; PF00400; WD40; 5.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 13..203
FT /note="Autophagy-related protein 16"
FT /evidence="ECO:0000259|Pfam:PF08614"
FT REPEAT 318..351
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 362..403
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 404..445
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 540..571
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 573..607
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 242..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 107..227
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 245..259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 607 AA; 68511 MW; 9911CF380D35D60B CRC64;
MAGRRVECVW KRHVAQQLKQ RDRVQRQAFE EIIQQYNRLL EKSDLQAVLS ERLQTEKYEL
QSRHDLSPGA ELSHCDLLQQ EMSRMRIKHQ EELTELHKKR GELAQSVIEL NNQIQQKDKE
IQNNEAKMLE YQQQISQLEG DCRELRNCLS DLERANQMLR DEYDALQITF SALEEKLRKT
TEDNQELVTR WMAEKAQEAN RLNAENEKDC RRRQAKLQKE LADAAKEPLP VDMDDDIEVL
SEETGKGTGE TSPNHPVRGT PRRASQLPPG NLLDSITNIF GVVRRRSLNS HGSPPDMAET
PSGVCADVRV PSTALHLFDA HEGEVNAVRF SPGSRQFATG GMDRRVKLWE VIAGHCECKG
TLMGSNAGIT SIEFDSTGSY LLAASNDFAS RIWTVDDYRL RHTLTGHSGK VLSARFLLDN
ARVVSGSYDR TLKLWDLRSK VCTKTVFAGS SCNDIVCTEQ CVMSGHFDKK VRFWDIRAES
TVCELELLGR VTSLDLNHDR TELLTCSRDD LLKIIDLRNN AVRQTFSADH FKCGSDFTRV
TFSPDGSYVA GGSADGVLYV WNVLTGKVEI KLDKGHSSSI NAVSWSPSGS YVLSVEKSSK
AVLWSDM
//
