ID A0A2D0SW36_ICTPU Unreviewed; 201 AA.
AC A0A2D0SW36;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=adenine phosphoribosyltransferase {ECO:0000256|ARBA:ARBA00011893};
DE EC=2.4.2.7 {ECO:0000256|ARBA:ARBA00011893};
GN Name=zgc:174895 {ECO:0000313|RefSeq:XP_017346903.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017346903.1};
RN [1] {ECO:0000313|RefSeq:XP_017346903.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017346903.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate +
CC adenine; Xref=Rhea:RHEA:16609, ChEBI:CHEBI:16708, ChEBI:CHEBI:33019,
CC ChEBI:CHEBI:58017, ChEBI:CHEBI:456215; EC=2.4.2.7;
CC Evidence={ECO:0000256|ARBA:ARBA00000868};
CC -!- PATHWAY: Purine metabolism; AMP biosynthesis via salvage pathway; AMP
CC from adenine: step 1/1. {ECO:0000256|ARBA:ARBA00004659}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the purine/pyrimidine phosphoribosyltransferase
CC family. {ECO:0000256|ARBA:ARBA00008391}.
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DR RefSeq; XP_017346903.1; XM_017491414.3.
DR AlphaFoldDB; A0A2D0SW36; -.
DR STRING; 7998.ENSIPUP00000025795; -.
DR Ensembl; ENSIPUT00000026873; ENSIPUP00000025803; ENSIPUG00000017468.
DR GeneID; 108278204; -.
DR KEGG; ipu:108278204; -.
DR OMA; SHCIPEG; -.
DR OrthoDB; 5389988at2759; -.
DR Proteomes; UP000221080; Chromosome 17.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR CDD; cd06223; PRTases_typeI; 1.
DR Gene3D; 3.40.50.2020; -; 1.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR029057; PRTase-like.
DR PANTHER; PTHR11776; ADENINE PHOSPHORIBOSYLTRANSFERASE; 1.
DR PANTHER; PTHR11776:SF7; PRIBOSYLTRAN DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00156; Pribosyltran; 1.
DR SUPFAM; SSF53271; PRTase-like; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000313|RefSeq:XP_017346903.1};
KW Transferase {ECO:0000313|RefSeq:XP_017346903.1}.
FT DOMAIN 44..179
FT /note="Phosphoribosyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00156"
SQ SEQUENCE 201 AA; 22329 MW; F6E18F70A2E9E5CA CRC64;
MNVFAVPQKR DKGWYLSLMA PNTKGPKFAW LDPSRLYCNS QALSDCVKDL LKPFHSDSID
LVAGIDAMGF ILGSAIATTL EKGFLAIRKA GHLCVETQTQ EYTDYSGRNK LMEVRDDVLK
PGLRVLIVDQ WIETGGTMKA AIKLVEKQGA SVVGVAAVAI ENSEGGKWIK ENYKHSHCIP
KAIQSQIDRQ YLEFFNSNFN S
//
