ID A0A2D0SZL6_ICTPU Unreviewed; 800 AA.
AC A0A2D0SZL6;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2023, sequence version 2.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=FYN-binding protein 1 isoform X2 {ECO:0000313|RefSeq:XP_017347971.2};
GN Name=fybb {ECO:0000313|RefSeq:XP_017347971.2};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017347971.2};
RN [1] {ECO:0000313|RefSeq:XP_017347971.2}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017347971.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_017347971.2; XM_017492482.3.
DR AlphaFoldDB; A0A2D0SZL6; -.
DR OrthoDB; 5403214at2759; -.
DR Proteomes; UP000221080; Chromosome 18.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:InterPro.
DR Gene3D; 2.30.30.40; SH3 Domains; 2.
DR InterPro; IPR043443; FYB1/2-like.
DR InterPro; IPR029294; hSH3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR16830:SF19; FYN-BINDING PROTEIN ISOFORM X1-RELATED; 1.
DR PANTHER; PTHR16830; SH2 CONTAINING ADAPTOR PRAM-1 RELATED; 1.
DR Pfam; PF14603; hSH3; 2.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 503..564
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 34..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 85..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 147..499
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 565..628
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 647..710
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 147..169
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 223..239
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 273..287
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..305
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 364..379
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 383..412
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 454..496
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 692..710
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 800 AA; 87869 MW; 1E5B8C11FE2CF46A CRC64;
MTEMEQVIGF HVSCSSSAGR GSSKQCRFVR RQTASHTHTH THTHKHARSG AGEIRHQTQQ
EPTTIMDNKS DVRAIRARFQ TAGVSMEGSG AARPKTTVHP TLSGPMVPSK KPALEVSLSG
SAAAAAAAAN STNPRPSYLK NIVSNNSAPE PWESSKSKAL VSKFENANAN EDSKPPFAKP
LKPKPPDWNQ NSEQKPKIPL QKPLITEAKN VFPKPPVTTK PFKSPKPENN ESTVNTIPTP
PKTPAAPKPK SSINLLWQQA GEEKEEDNTA KPFSRANLKN SSFHTAHNRF NKPEEPAKDE
SKSQSSKESQ VPGPSVAQKK PSYKTKPSGL DAQTVKDPLA PKKNPLTNLL ALGSAPSKPN
RPPKVNLEKF KKAAEPPSEG PEIKKGGPLP PPPPASHPST QAAPILPPRP PGPKMETEEE
YDDVGDLHDS SFGNSGRGDE GSGSDGETYE ELDGWSTPEV KEQEKKREKE EKRRAEQEKK
DQKEREKKEQ EARKKFKLSG PLQVIHKVKA RVDCKGGRND LSFKQGDSID ILRITDNPEG
RWLARTQDGS CGYVKTESVQ IDFDTLKNQT RPLPENDGDV YDDVGSQEDN SRSNSGPGVV
LPPPPEGPDD IYDDLDDSSL NVSPEPRSLP KARSFIRMLT PSDWRKSPVH INVVPPPPQF
SPESNPGAEE IYDDVDTPQP PSSLPPSKSK PAKPEAKTDD PKKQKKFEKE EKEFRKKFKF
DGEIKVLYQA TVISNKKGSG KDLAVQAGDI LDVISNLDND KLICRNKEGK FGYVLNSNLQ
SDDNDIYDDV GDDCIYDNDN
//
