ID   A0A2D0T0R5_ICTPU        Unreviewed;       705 AA.
AC   A0A2D0T0R5;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Cytoplasmic polyadenylation element-binding protein 4b isoform X2 {ECO:0000313|RefSeq:XP_017348376.1};
GN   Name=cpeb4b {ECO:0000313|RefSeq:XP_017348376.1};
OS   Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC   Ictaluridae; Ictalurus.
OX   NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017348376.1};
RN   [1] {ECO:0000313|RefSeq:XP_017348376.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_017348376.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the RRM CPEB family.
CC       {ECO:0000256|ARBA:ARBA00010347}.
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DR   RefSeq; XP_017348376.1; XM_017492887.2.
DR   AlphaFoldDB; A0A2D0T0R5; -.
DR   Ensembl; ENSIPUT00000008430; ENSIPUP00000008074; ENSIPUG00000005518.
DR   GeneID; 108279011; -.
DR   CTD; 100333151; -.
DR   OrthoDB; 5395046at2759; -.
DR   Proteomes; UP000221080; Chromosome 18.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IEA:InterPro.
DR   GO; GO:0045182; F:translation regulator activity; IEA:InterPro.
DR   CDD; cd19757; Bbox1; 1.
DR   CDD; cd12724; RRM1_CPEB2_like; 1.
DR   CDD; cd12726; RRM2_CPEB2_like; 1.
DR   Gene3D; 3.30.70.330; -; 2.
DR   Gene3D; 4.10.640.40; Cytoplasmic polyadenylation element-binding protein, ZZ domain; 1.
DR   InterPro; IPR032296; CEBP_ZZ.
DR   InterPro; IPR038446; CEBP_ZZ_sf.
DR   InterPro; IPR034819; CPEB.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   PANTHER; PTHR12566; CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB; 1.
DR   PANTHER; PTHR12566:SF2; CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 4; 1.
DR   Pfam; PF16366; CEBP_ZZ; 1.
DR   Pfam; PF16367; RRM_7; 1.
DR   SMART; SM00360; RRM; 2.
DR   SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR   PROSITE; PS50102; RRM; 2.
PE   3: Inferred from homology;
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW   ProRule:PRU00176}.
FT   DOMAIN          448..535
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   DOMAIN          556..634
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   REGION          26..60
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          79..169
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          218..298
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          324..354
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        33..56
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        83..107
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        111..137
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        152..169
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        324..352
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   705 AA;  77203 MW;  83CA03117EC048A7 CRC64;
     MGDYGFGVLV QNNTGNKSAF PVRIHPHLQP PHHHQNVTPS PAAFINSTTP GNGSTAGSPW
     LFPAAAAHTN VQDDLGADKP KAQQQELQET QEKQQQQQQQ LSPVHQESGI ISELEKARSD
     ESKSENGTSE GTSGKEKLRL ESPVLSPFDY QEPSGLGTTV QSSTSSSSLT SFNNWSAAIA
     PTPSAIVNED VGFFTPASNG PLLFQNFSHH VGPGFGGSFS PQIGAVSQHH APPPHPHFQH
     QQHRRSPASP HNPPPFPHRG ATFGQLPHLS SGLSKPPSPW GAYPSPSPSP SSASWSPGGG
     AYGSGTGWGG SRGADFRRGL NGAVTPLSSV SPLKKTFPNN HSASQKYTRP GATFTPKTWM
     DETVGRSDNV FPFQERNRSF DGFSMHSLEN SLIDIMRAEQ DTLKGHSSLF PMEDGFPDEE
     RAEQSLPGLG SPHCFPHQNG ERVERYSRKV FVGGLPPDID EDEITASFRR FGHLFVDWPH
     KAESKSYFPP KGYAFLLFQD ESSVQALIDA CIEEDGKLYL CVSSPTIKDK PVQIRPWNLN
     DSDFVMDGSQ PLDPRKTIFV GGVPRPLRAV ELAMIMDRLY GGVCYAGIDT DPELKYPKGA
     GRVAFSNQQS YIAAISARFV QLQHGEIDKR VEVKPYVLDD QLCDECQGTR CGGKFAPFFC
     ANVTCLQYYC EYCWAAIHSR AGREFHKPLV KEGGDRPRHI SFCWN
//