ID A0A2D0T8H7_ICTPU Unreviewed; 361 AA.
AC A0A2D0T8H7;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Homer protein homolog 3 {ECO:0000313|RefSeq:XP_017351184.1};
GN Name=LOC108280570 {ECO:0000313|RefSeq:XP_017351184.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017351184.1};
RN [1] {ECO:0000313|RefSeq:XP_017351184.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017351184.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Postsynaptic density {ECO:0000256|ARBA:ARBA00034105}. Synapse
CC {ECO:0000256|ARBA:ARBA00034103}.
CC -!- SIMILARITY: Belongs to the Homer family.
CC {ECO:0000256|ARBA:ARBA00023606}.
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DR RefSeq; XP_017351184.1; XM_017495695.3.
DR AlphaFoldDB; A0A2D0T8H7; -.
DR Ensembl; ENSIPUT00000007592; ENSIPUP00000007277; ENSIPUG00000005017.
DR GeneID; 108280570; -.
DR KEGG; ipu:108280570; -.
DR OrthoDB; 5490527at2759; -.
DR Proteomes; UP000221080; Chromosome 20.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.
DR GO; GO:0035256; F:G protein-coupled glutamate receptor binding; IEA:InterPro.
DR GO; GO:0007216; P:G protein-coupled glutamate receptor signaling pathway; IEA:InterPro.
DR CDD; cd01206; EVH1_Homer_Vesl; 1.
DR Gene3D; 1.20.5.1700; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR045027; Homer.
DR InterPro; IPR044100; Homer_EVH1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR000697; WH1/EVH1_dom.
DR PANTHER; PTHR10918; HOMER; 1.
DR PANTHER; PTHR10918:SF4; HOMER PROTEIN HOMOLOG 3; 1.
DR Pfam; PF00568; WH1; 1.
DR SMART; SM00461; WH1; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50229; WH1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Synapse {ECO:0000256|ARBA:ARBA00023018}.
FT DOMAIN 4..116
FT /note="WH1"
FT /evidence="ECO:0000259|PROSITE:PS50229"
FT COILED 203..333
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 361 AA; 41386 MW; 02BA9A3282F57E46 CRC64;
MFPSHREREQ PIFSTRAHVF QIDPATKRNW IPASKHAVTV SFFYDANRHA YRIISVGGTK
AIINSTITHN MTFTKTSQKF GQWADSRANT VYGLGFATEQ QLNQFCERFK EVKEAARLAR
EKSQDKMELA NVALNIAAPQ DLSDELQSPP VMCVNGPDDK LFRSQSADIT LSSEKERIKK
MLSEGSICEI NLEAELFTLQ DSNAKLVAAL HEANANVEQW KKQLAAYQEE TERLREQVAD
LEAHGGQGPS DMLKDELTQS LEELEALLKA KDEEIRILQA KKSNFHEMEQ EREEAIHRLQ
ELEMRNMDLE RRVQSAEQSL ASTLEDRDRT ENEVQRVIQI LDIKLFDLND LRQSLVKLLE
K
//
