ID A0A2D0TBF0_ICTPU Unreviewed; 504 AA.
AC A0A2D0TBF0;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2023, sequence version 2.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Interferon regulatory factor 6 isoform X2 {ECO:0000313|RefSeq:XP_017352110.2, ECO:0000313|RefSeq:XP_053530105.1};
GN Name=irf6 {ECO:0000313|RefSeq:XP_017352110.2,
GN ECO:0000313|RefSeq:XP_053530105.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|RefSeq:XP_017352110.2};
RN [1] {ECO:0000313|RefSeq:XP_017352110.2, ECO:0000313|RefSeq:XP_053530105.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017352110.2,
RC ECO:0000313|RefSeq:XP_053530105.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_017352110.2; XM_017496621.3.
DR RefSeq; XP_053530105.1; XM_053674130.1.
DR OrthoDB; 3740806at2759; -.
DR Proteomes; UP000221080; Chromosome 21.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:UniProt.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd00103; IRF; 1.
DR Gene3D; 2.60.200.10; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR019817; Interferon_reg_fac_CS.
DR InterPro; IPR001346; Interferon_reg_fact_DNA-bd_dom.
DR InterPro; IPR019471; Interferon_reg_factor-3.
DR InterPro; IPR017855; SMAD-like_dom_sf.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11949; INTERFERON REGULATORY FACTOR; 1.
DR PANTHER; PTHR11949:SF9; INTERFERON REGULATORY FACTOR 6; 1.
DR Pfam; PF00605; IRF; 1.
DR Pfam; PF10401; IRF-3; 1.
DR PRINTS; PR00267; INTFRNREGFCT.
DR SMART; SM00348; IRF; 1.
DR SMART; SM01243; IRF-3; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00601; IRF_1; 1.
DR PROSITE; PS51507; IRF_2; 1.
PE 4: Predicted;
FT DOMAIN 7..115
FT /note="IRF tryptophan pentad repeat"
FT /evidence="ECO:0000259|PROSITE:PS51507"
FT REGION 122..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 145..162
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..211
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 504 AA; 56530 MW; FC9BDC93C10C142A CRC64;
MSVHPRRVRL KPWLVAQVDN GTFPGLVWLD REAKRFQIPW KHATRHTAQQ EEENTLFKAW
AVETGKFQEG VDEPDPAKWK AQLRCALNKS REFNLIYDGT KEVPMNPLKI YDVCDIPVPL
INPGSTGSAP AYDSDGEDDD VPDTPEPPPP PYHPPVGGSP LAPPVWTSPG STSPLQPSPL
QPSPLQPSPL QPSPMQPSPM QPSPMQPSPQ VWPKKEPQDV EMNTPAAMEI QPASNMDTQP
ITDVLFTTPE TWISSLPMTD LEVQFYYRGK EVCPGVTVSN PQGCRLFYGD LGPMVNQEEL
FGPVSLEQLR FPSTEHITND KQRLFTNRLL DVMDRGLILE ISAHDIYAVR LCQCKVYWSG
PCGPNANTPN LIERQRRVKL FCLETFLSSV IAHQRGQSPS LPQFDIHLCF GEEWPDGRPR
ERKLIMVQVV PVVARIITEM FSSDGTRSFD SSSVRLQISV PDIKDNIVTQ LKQLYRLLQN
HQGNEAWPLP SAGHAPLSHP LHAQ
//
