ID A0A2D1U628_9SPHI Unreviewed; 590 AA.
AC A0A2D1U628;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Signal peptide peptidase SppA {ECO:0000313|EMBL:ATP57071.1};
GN Name=sppA {ECO:0000313|EMBL:ATP57071.1};
GN ORFNames=CPT03_11600 {ECO:0000313|EMBL:ATP57071.1};
OS Pedobacter ginsengisoli.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Pedobacter.
OX NCBI_TaxID=363852 {ECO:0000313|EMBL:ATP57071.1, ECO:0000313|Proteomes:UP000223749};
RN [1] {ECO:0000313|EMBL:ATP57071.1, ECO:0000313|Proteomes:UP000223749}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T01R-27 {ECO:0000313|EMBL:ATP57071.1,
RC ECO:0000313|Proteomes:UP000223749};
RA Weon H.-Y., Lee S.A., Sang M.K., Song J.;
RT "Whole genome of Pedobacter ginsengisoli T01R-27 isolated from tomato
RT rhizosphere.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S49 family.
CC {ECO:0000256|ARBA:ARBA00008683}.
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DR EMBL; CP024091; ATP57071.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2D1U628; -.
DR KEGG; pgs:CPT03_11600; -.
DR OrthoDB; 9764363at2; -.
DR Proteomes; UP000223749; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006465; P:signal peptide processing; IEA:InterPro.
DR CDD; cd07018; S49_SppA_67K_type; 1.
DR CDD; cd07023; S49_Sppa_N_C; 1.
DR Gene3D; 6.20.330.10; -; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR004634; Pept_S49_pIV.
DR InterPro; IPR004635; Pept_S49_SppA.
DR InterPro; IPR002142; Peptidase_S49.
DR InterPro; IPR047217; S49_SppA_67K_type_N.
DR InterPro; IPR047272; S49_SppA_C.
DR NCBIfam; TIGR00705; SppA_67K; 1.
DR NCBIfam; TIGR00706; SppA_dom; 1.
DR PANTHER; PTHR33209; PROTEASE 4; 1.
DR PANTHER; PTHR33209:SF1; SERINE PROTEASE SPPA, CHLOROPLASTIC; 1.
DR Pfam; PF01343; Peptidase_S49; 2.
DR PIRSF; PIRSF001217; Protease_4_SppA; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000223749};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 127..278
FT /note="Peptidase S49"
FT /evidence="ECO:0000259|Pfam:PF01343"
FT DOMAIN 375..526
FT /note="Peptidase S49"
FT /evidence="ECO:0000259|Pfam:PF01343"
FT ACT_SITE 195
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001217-1"
FT ACT_SITE 390
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR001217-1"
SQ SEQUENCE 590 AA; 64767 MW; 20F3D291FC1FE4D0 CRC64;
MREFFKYVFA TIVGVIISLV LFTLLFVVII VGVVSSLEGD KTVSVSSNSV LYLNLDQAIR
ERTPDDTFSN LPIVGGDGEK SIGFNDILKS LKKAKTDDNI KCIYLNVTSP NAGFATLREV
RNALIDFKTS KKKIIAYSEV YTQGAYYLAS AADKVYLNPE GALEFKGLSS QIMFFKGALD
KLGIEAQIIR VGSYKSAIEP FITDKMSDKN REQVTAYLTG LYNTFLEGIG ESRHISTPTL
HQIADDYKIQ QPKDAVAYKL IDGLKYKDEI LDELKTLSGK DKKSNISSIT INDYAKNVNT
DIGESSKNKV AVIYADGDIV GGEGSNAQIG SERLSRTIRK ARLDSNIKAI VLRVNSPGGS
ALASDVIWRE IILAKKVKPV IASFGDVAAS GGYYIACAAD SIFVQPNTIT GSIGVFGVIP
NFQKLLNTKL GITFDGVKTG KYADIMSTNR PLTDGERLII QTDVNRVYET FIAHVSEGRK
RTKAYIDSIG GGRVWIGTDA VKIGLADRTG SFNDAITSAA KKAKVKDYRV VEYPEMISPL
KSFMDSSTDK VRTYYAKQEL GENYPIYQQI KSTISKSGVQ TRMPFEIIVK
//
