ID   A0A2D2B187_9CAUL        Unreviewed;       391 AA.
AC   A0A2D2B187;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) {ECO:0000256|ARBA:ARBA00038858};
DE            EC=5.1.3.14 {ECO:0000256|ARBA:ARBA00038858};
GN   ORFNames=CSW64_17180 {ECO:0000313|EMBL:ATQ43996.1};
OS   Caulobacter mirabilis.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC   Caulobacteraceae; Caulobacter.
OX   NCBI_TaxID=69666 {ECO:0000313|EMBL:ATQ43996.1, ECO:0000313|Proteomes:UP000228945};
RN   [1] {ECO:0000313|EMBL:ATQ43996.1, ECO:0000313|Proteomes:UP000228945}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FWC 38 {ECO:0000313|EMBL:ATQ43996.1,
RC   ECO:0000313|Proteomes:UP000228945};
RA   Fiebig A., Crosson S.;
RT   "Genome sequence of Caulobacter mirabilis FWC38.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-
CC         mannosamine; Xref=Rhea:RHEA:17213, ChEBI:CHEBI:57705,
CC         ChEBI:CHEBI:68623; EC=5.1.3.14;
CC         Evidence={ECO:0000256|ARBA:ARBA00036080};
CC   -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC       {ECO:0000256|ARBA:ARBA00038209, ECO:0000256|RuleBase:RU003513}.
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DR   EMBL; CP024201; ATQ43996.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2D2B187; -.
DR   KEGG; cmb:CSW64_17180; -.
DR   OrthoDB; 9803238at2; -.
DR   Proteomes; UP000228945; Chromosome.
DR   GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:InterPro.
DR   CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR   Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR   InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR   InterPro; IPR029767; WecB-like.
DR   NCBIfam; TIGR00236; wecB; 1.
DR   PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR   PANTHER; PTHR43174:SF2; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR   Pfam; PF02350; Epimerase_2; 1.
DR   SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE   3: Inferred from homology;
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU003513};
KW   Reference proteome {ECO:0000313|Proteomes:UP000228945}.
FT   DOMAIN          23..367
FT                   /note="UDP-N-acetylglucosamine 2-epimerase"
FT                   /evidence="ECO:0000259|Pfam:PF02350"
SQ   SEQUENCE   391 AA;  42342 MW;  DF411C39EE939008 CRC64;
     MRVLSIFGTR PEAIKMAPVV LRLSADPEIE SIVCTTGQHR QMLDQMLGAF GVTPDVDLGV
     MTQGQSLNAL TGQILTTLDG VLEQTKPDRV LVHGDTATAM AASLAAFHRR IPVGHVEAGL
     RTYDLQKPWP EEMNRRFVDI VSDLMFAPTE GSRENLAGER LGGRVFVTGN TVIDALHHAQ
     AILARNAAMR ARIDAALPRI DPAKRLVLVT GHRRESFGDG FRDICAALLR LAERSDVEII
     YPVHLNPNVR EPVMQALGGR DNIHLIAPQD YFPFVRLMQR ADVILTDSGG VQEEAPALGK
     PVLVMRDVTE RPEAVAAGAA ELVGTAPDSI VAAVTRVLDE EAVRLAFARG RSPYGDGRAA
     DRIASALLGV PFDEFDMASP SQTAVMERLS A
//