ID A0A2D3UUW3_9PEZI Unreviewed; 851 AA.
AC A0A2D3UUW3;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=Beta-mannosidase B {ECO:0000256|ARBA:ARBA00041069};
DE EC=3.2.1.25 {ECO:0000256|ARBA:ARBA00012754};
DE AltName: Full=Mannanase B {ECO:0000256|ARBA:ARBA00041614};
GN ORFNames=RCC_04863 {ECO:0000313|EMBL:CZT19018.1};
OS Ramularia collo-cygni.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Ramularia.
OX NCBI_TaxID=112498 {ECO:0000313|EMBL:CZT19018.1, ECO:0000313|Proteomes:UP000225277};
RN [1] {ECO:0000313|EMBL:CZT19018.1, ECO:0000313|Proteomes:UP000225277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=URUG2 {ECO:0000313|EMBL:CZT19018.1,
RC ECO:0000313|Proteomes:UP000225277};
RA Ploux O.;
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-mannose residues
CC in beta-D-mannosides.; EC=3.2.1.25;
CC Evidence={ECO:0000256|ARBA:ARBA00000829};
CC -!- PATHWAY: Glycan metabolism; N-glycan degradation.
CC {ECO:0000256|ARBA:ARBA00004740}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family. Beta-
CC mannosidase B subfamily. {ECO:0000256|ARBA:ARBA00038429}.
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DR EMBL; FJUY01000006; CZT19018.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2D3UUW3; -.
DR STRING; 112498.A0A2D3UUW3; -.
DR OrthoDB; 2504097at2759; -.
DR Proteomes; UP000225277; Unassembled WGS sequence.
DR GO; GO:0004567; F:beta-mannosidase activity; IEA:UniProt.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR041447; Mannosidase_ig.
DR PANTHER; PTHR43730; BETA-MANNOSIDASE; 1.
DR PANTHER; PTHR43730:SF1; BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF17786; Mannosidase_ig; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 2.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000225277}.
FT DOMAIN 194..298
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 693..779
FT /note="Mannosidase Ig/CBM-like"
FT /evidence="ECO:0000259|Pfam:PF17786"
SQ SEQUENCE 851 AA; 97244 MW; 37FF48D9D3BEE892 CRC64;
MAQTMQTQEL TSGWSFKQTD TEEWMPVAKV PTNVHLDLMD QKIIEDPFLG FNELKCEWVG
EKAWTYKVTL PSVPATERGT KHVLAFDGLD TFANVKLNGK TVLESDNMWI MHRVDVTDKL
QPENENVLEI DFKSAMVEAR KIKEAHPEHK WVGFNGDMAR LAVRKAQYHW GWDWGPVLSP
CGPWRAVRLE TYHARVEDLR IDYEVDASFK KVTGTITAFV EGQSGKVVEF SGSLGGSPVF
KATSEVDSNG QAKAEFHINE PKLWYPHGYG EQPLYNITAT VTSGGHALDS ITKRTGFRKG
ELIQEPDEIG KTFFFRFNGI DVFCGGSDWI PADSFTPRIT EEKYRKWLEM MVDGYQLMIR
IWGGGIWEED IFYDICDELG ILVWQDFMFG CGNYPCFPEI LESIEKECVC QTKRLRHHPS
MAIYAGNNED YQVQEQMGLT YNYEDKDPQS WLQTDFPARY IYEKVPYPDP QRALILTALQ
LLPDVVAAHT PHIPYHPGSP WGDGKISSDP TIGDMHQWNV WHGTQEKYQI FDTLGGRFNS
EFGMEAFPHI DTIKAYVTDP TQLYPQSHMI DFHNKADGHE RRIATYLVEN FRTETDLEKF
IHLTQLSQAE ALMFGYRGWR QQWGQKRFCG GALLWQLNDC WPVTSWSIVD YYLRKKPAYY
ALRRVLAPIA VAVKRAHHDW SVVHARPAKA IDYECWVASF ETKEVTATVE LRYISIATGK
EIKEKVLKKD VQIQANGTTN IFKGTIDNVN EEQHVLAARI WVDGKIVSRD VDWPQPLKYL
DFADRELEVT PKGNTITIKA GKPTKGLVFE EREGVLVNDS AIDVVPGDEQ VVTVKGIGAN
DKALGWTYLG K
//
