ID   A0A2D3UWR5_9PEZI        Unreviewed;       449 AA.
AC   A0A2D3UWR5;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 12.
DE   SubName: Full=Probable saccharopine reductase {ECO:0000313|EMBL:CZT21241.1};
GN   ORFNames=RCC_07104 {ECO:0000313|EMBL:CZT21241.1};
OS   Ramularia collo-cygni.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Ramularia.
OX   NCBI_TaxID=112498 {ECO:0000313|EMBL:CZT21241.1, ECO:0000313|Proteomes:UP000225277};
RN   [1] {ECO:0000313|EMBL:CZT21241.1, ECO:0000313|Proteomes:UP000225277}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=URUG2 {ECO:0000313|EMBL:CZT21241.1,
RC   ECO:0000313|Proteomes:UP000225277};
RA   Ploux O.;
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FJUY01000011; CZT21241.1; -; Genomic_DNA.
DR   STRING; 112498.A0A2D3UWR5; -.
DR   OrthoDB; 2184985at2759; -.
DR   Proteomes; UP000225277; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1870.10; Domain 3, Saccharopine reductase; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR032095; Sacchrp_dh-like_C.
DR   InterPro; IPR005097; Sacchrp_dh_NADP.
DR   PANTHER; PTHR11133:SF25; ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR11133; SACCHAROPINE DEHYDROGENASE; 1.
DR   Pfam; PF16653; Sacchrp_dh_C; 1.
DR   Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR   SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00023154};
KW   Lysine biosynthesis {ECO:0000256|ARBA:ARBA00023154};
KW   NADP {ECO:0000256|ARBA:ARBA00022857};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000225277}.
FT   DOMAIN          6..119
FT                   /note="Saccharopine dehydrogenase NADP binding"
FT                   /evidence="ECO:0000259|Pfam:PF03435"
FT   DOMAIN          124..441
FT                   /note="Saccharopine dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16653"
SQ   SEQUENCE   449 AA;  49246 MW;  1085A4ED956EA46D CRC64;
     MAPQKVLLLG AGFVTRPTAV ELDKAGVEVT VACRTLESSK KLAQGLKHAN AITVDVSNAE
     ALEKEISKVD LVISLIPYTF HAQVIKAAIN QKKNVVTTSY VSEAMMALDK EAKEAGITVX
     NEIGLDPGLD HLYAVKTIDE VHKAGGKITG FLSYCGGLPA PESSDNPLGY KFSWSPRGVL
     LAARNTATFF KDGKKDSVSG ADLMSTAKPY FIYPGYAFEA YPNRDSTPFR ERYDIPEAQT
     LIRGTLRYQG NPAFVQAFQE LGMLSDQEHD FLKQPISWKE AFGKIVGATS HTEQDLTWAV
     SSKAKFRSTE DKDRILAGLR WFGLFSDDKI EPRGTPLDCL CATLEKKMQY TEGERDFVML
     QHKFEIEWAD GKKETRTSTL CDYGEKEGSG GYSAMARLVG VPCAVAVLLI LNGEIKDKGI
     LAPVTPALAE PIRLKLLDYG IELTEKTLA
//