ID   A0A2D6FKD2_9BACT        Unreviewed;       856 AA.
AC   A0A2D6FKD2;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   13-SEP-2023, entry version 14.
DE   RecName: Full=DOD-type homing endonuclease domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CMI54_03010 {ECO:0000313|EMBL:MAF43127.1};
OS   Parcubacteria group bacterium.
OC   Bacteria.
OX   NCBI_TaxID=2026774 {ECO:0000313|EMBL:MAF43127.1, ECO:0000313|Proteomes:UP000221304};
RN   [1] {ECO:0000313|Proteomes:UP000221304}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Tully B.J., Graham E.D., Heidelberg J.F.;
RT   "The Reconstruction of 2,631 Draft Metagenome-Assembled Genomes from the
RT   Global Oceans.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:MAF43127.1}.
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DR   EMBL; NYZL01000033; MAF43127.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2D6FKD2; -.
DR   Proteomes; UP000221304; Unassembled WGS sequence.
DR   GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR   GO; GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
DR   CDD; cd00081; Hint; 1.
DR   Gene3D; 2.170.16.10; Hedgehog/Intein (Hint) domain; 1.
DR   Gene3D; 3.10.28.10; Homing endonucleases; 1.
DR   InterPro; IPR036844; Hint_dom_sf.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR006142; INTEIN.
DR   InterPro; IPR030934; Intein_C.
DR   InterPro; IPR004042; Intein_endonuc.
DR   InterPro; IPR006141; Intein_N.
DR   InterPro; IPR004860; LAGLIDADG_2.
DR   InterPro; IPR007390; Spore_V_R.
DR   PANTHER; PTHR30029:SF2; STAGE V SPORULATION PROTEIN R; 1.
DR   PANTHER; PTHR30029; UNCHARACTERIZED; 1.
DR   Pfam; PF14528; LAGLIDADG_3; 1.
DR   Pfam; PF04293; SpoVR; 2.
DR   PRINTS; PR00379; INTEIN.
DR   SUPFAM; SSF51294; Hedgehog/intein (Hint) domain; 1.
DR   SUPFAM; SSF55608; Homing endonucleases; 1.
DR   PROSITE; PS50818; INTEIN_C_TER; 1.
DR   PROSITE; PS50819; INTEIN_ENDONUCLEASE; 1.
DR   PROSITE; PS50817; INTEIN_N_TER; 1.
PE   4: Predicted;
KW   Autocatalytic cleavage {ECO:0000256|ARBA:ARBA00022813};
KW   Protein splicing {ECO:0000256|ARBA:ARBA00023000}.
FT   DOMAIN          439..579
FT                   /note="DOD-type homing endonuclease"
FT                   /evidence="ECO:0000259|PROSITE:PS50819"
FT   DOMAIN          653..675
FT                   /note="Intein C-terminal splicing"
FT                   /evidence="ECO:0000259|PROSITE:PS50818"
SQ   SEQUENCE   856 AA;  99861 MW;  1784BA72F2F43889 CRC64;
     MNTWTESDLF HWDEKICRAA EDLGLDWHPI DYEIIDYQEM LGAMAYVGLP THYRHWSYGK
     EYERTHTLYN MGQTGLPYEM IINSNPSIAY LMRENALDTH ILTMAHCVGH SDFFKNNRMF
     VNTDPNNIID TFKAAAKYVR KLIEDPSVGV DKVENILDAA HSIKYQVPRQ PGIKYKTRDQ
     IIAIEKKKMS ENPKYNPNLN KIPLRPEYNL LKFVAEHSKH LKEWERNLIL IVEESSKYFI
     PQALTKVMNE GWACLIKGNL INTSMGLLPI EDIVENKKTV DVYDGIEYKK VYNWFKNKGV
     KRIKIITEAG YELHGGNNHK IYTNNKWSPL SELAPGDEIE ILTSESEPWT SGYCRLNYEP
     PQIVTKTQIL KENSLDPRTY RKFELGKIVT NKRNALERCK IVEHKLLSRT SKCGASFGKR
     ANAMDITLPP YLTEDLGYLL GMITGDGGFH SKNKNHQKTK CYITTGDYET VVKISEIIKK
     CFGYEPRVQP LQNKWSINIY SVILNHFLMS NFGFNSGKTS HTKKIPDLIF QSPKKVVVNF
     LRGYYDADGC AAKDGSVILS STSKILIRQT QDLLLRFGII TKLNKQKNYN PQKHNTCYQL
     YLAGEHSRTF HNEITFGLQR KRRIQENWLS KKKWFKKQSN KTKIKKIVHD IGDTYDFSVE
     DTHRYRSGAF LNHNCTIHHK IVNELRLPDS LHLPFIKLHN QVVRPHLGTL NPYHLGFKLF
     EKIINEKGFE EAMMVREIHN DISFLRFYID EEFMRENNYF SYSFKKDKKA STIDEISDKE
     GWEAVRDQMI QNIGLNRVPI VYVDEIEKNN ILSLIHEHDG RDLDLTYANK VHRHIGTLWG
     DELRLFSIVE NEIWEF
//