ID   A0A2D8P6Q8_9RHOB        Unreviewed;      1004 AA.
AC   A0A2D8P6Q8;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=Sarcosine oxidase subunit alpha {ECO:0000313|EMBL:MAM61141.1};
GN   ORFNames=CMH11_06585 {ECO:0000313|EMBL:MAM61141.1};
OS   Maritimibacter sp.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Maritimibacter.
OX   NCBI_TaxID=2003363 {ECO:0000313|EMBL:MAM61141.1, ECO:0000313|Proteomes:UP000224593};
RN   [1] {ECO:0000313|Proteomes:UP000224593}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Tully B.J., Graham E.D., Heidelberg J.F.;
RT   "The Reconstruction of 2,631 Draft Metagenome-Assembled Genomes from the
RT   Global Oceans.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:MAM61141.1}.
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DR   EMBL; NZNT01000015; MAM61141.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2D8P6Q8; -.
DR   Proteomes; UP000224593; Unassembled WGS sequence.
DR   GO; GO:0008115; F:sarcosine oxidase activity; IEA:InterPro.
DR   GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR   Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 3.
DR   InterPro; IPR042204; 2Fe-2S-bd_N.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR028896; GCST/YgfZ/DmdA.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR006277; Sarcosine_oxidase_asu.
DR   InterPro; IPR041117; SoxA_A3.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   NCBIfam; TIGR01372; soxA; 1.
DR   PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR   Pfam; PF13510; Fer2_4; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   Pfam; PF17806; SO_alpha_A3; 1.
DR   PIRSF; PIRSF037980; SoxA; 1.
DR   PRINTS; PR00368; FADPNR.
DR   PRINTS; PR00469; PNDRDTASEII.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          170..422
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
FT   DOMAIN          521..603
FT                   /note="SoxA A3"
FT                   /evidence="ECO:0000259|Pfam:PF17806"
FT   DOMAIN          618..883
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          909..996
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   1004 AA;  108571 MW;  DC0BC0DA7075CB2D CRC64;
     MSHRLDGKGR LIDRSKQLRF TFNGKSMTGY EGDTLASALL GAGQSVMGRS FKYHRPRGVV
     AAGVEEPNAL MNLGRGGRFE PNQRATTTPL FDGLTATSQN HWPSLDFDVG AVNDMAARFL
     PAGFYYKTFM FPRFAWKHVF EPFIRKSAGL GQSPTEPDAD RYEHAYHHTD VLVIGGGVAG
     LTAARAAGAG GAKVMVLEQT AHWGGRAPVD GGEIDGTDPE TWVNSAVEGL ENAQNVTLRP
     NCMGAGVYDH GYVLGYERVA ETTPGDGRPR HRLWRIRAKQ IVTATGAIER PLSFPGNDVP
     GVMLASAVRD YVVNWGVAPG KRTVIVTNND DAYLTALALK AAKLEVPAII DVRPTLMGPL
     AEKARKAGIR LMSGKALVGV KGKKGVTAVM VSDLEGKASP EAIDCDCVAM SGGWSPVVHL
     WSHCGGKLTW DDHEAIFKPD PTRPPLGADG QAFVATAGNA SGAMGLAEAL ADGHEVGRQA
     AKAAGGTLTR KAAPKAAETE RQPIKQVWIM PTSAGPDKRM KMWLDYQNDV KGSDVQLAAQ
     EGYQSVEHAK RYTTLGMATD QGKLSNINGL AVLSDALGQP IPQTGTTTFR PPYTPISMGA
     IAGEARGPLF QPIRRTPMHA LHETAGAVWE PVGHWRRPFC FARTGESDHE AVNREIVNTR
     ENVGMLDAST LGKILVTGPD AGKFLDMLYT NMMSTLPVGK CRYGLMCSEN GFLSDDGVVA
     RIDEQTWLCH TTTGGADRIH GHMEDWLQCE WWDWKVYTAN LTEQYAQVAV AGPKARKVLE
     ALGGMDVSKE AMPFMTWHDG TLADIPARVF RISFTGELSY EIAVPANRGA ELWEKVREAG
     AEHGIQPYGT EAMHIMRAEK GFIMIGDETD GTVIPQDLGL HWAISKKKED YLGKRAQERS
     FMASPDRWQL VGLQTLDGSV IPDGAYAVGE GRNANGQRNT IGRVTSTYYS PTIRKGIAMG
     LIHEGPQRMG EVVDFATLDG TGTVIKAKIV DTCFYDKEGA KADV
//