ID A0A2D8PAX5_9RHOB Unreviewed; 369 AA.
AC A0A2D8PAX5;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Cystathionine gamma-lyase {ECO:0000313|EMBL:MAM62552.1};
DE EC=4.4.1.1 {ECO:0000313|EMBL:MAM62552.1};
GN ORFNames=CMH11_13805 {ECO:0000313|EMBL:MAM62552.1};
OS Maritimibacter sp.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Maritimibacter.
OX NCBI_TaxID=2003363 {ECO:0000313|EMBL:MAM62552.1, ECO:0000313|Proteomes:UP000224593};
RN [1] {ECO:0000313|Proteomes:UP000224593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Tully B.J., Graham E.D., Heidelberg J.F.;
RT "The Reconstruction of 2,631 Draft Metagenome-Assembled Genomes from the
RT Global Oceans.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU362118};
CC -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC {ECO:0000256|RuleBase:RU362118}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MAM62552.1}.
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DR EMBL; NZNT01000025; MAM62552.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2D8PAX5; -.
DR Proteomes; UP000224593; Unassembled WGS sequence.
DR GO; GO:0004123; F:cystathionine gamma-lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0080146; F:L-cysteine desulfhydrase activity; IEA:UniProtKB-EC.
DR GO; GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IEA:UniProtKB-EC.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR11808:SF93; CYSTATHIONINE GAMMA-LYASE-RELATED; 1.
DR PANTHER; PTHR11808; TRANS-SULFURATION ENZYME FAMILY MEMBER; 1.
DR Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR PIRSF; PIRSF001434; CGS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:MAM62552.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR001434-2}.
FT MOD_RES 195
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ SEQUENCE 369 AA; 39178 MW; 5F2B3CB676259631 CRC64;
MSDKEKAARL HHMRTYGLAK GDPLALPLTM ASMFNLPGDP EPGVAGYGRM DNPTWEALED
ALGLIEDAPV RVFPSGMAAI AAVLFVVLKA GDRVLIPSDG YYTTRLLADG YLAKLGVEVV
TRPTVSIAEG GFEGFALVFL ETPSNPGLDV IDLAETCRAV RAAGGVSVVD NTTMTPFGQR
PLDLGADVVV ASDTKAPGGH SDVLIGHVAS RDADLIDGVS QWRKLSGAIP GPFEAWLLYR
SLATLELRFE RMCNSAEAIA ARLAGHPAVD AVRYPGLGED PAHDVASRQM TRFGFLIGVT
LADREAAERL INGCEMLAST TSFGGTHSTA ERRARWGDEV APGFVRLSVG VEPLEPLWAA
LNRALADLS
//
