ID A0A2D8R8U9_9GAMM Unreviewed; 1068 AA.
AC A0A2D8R8U9;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Sensor domain-containing diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN ORFNames=CME36_03740 {ECO:0000313|EMBL:MAM86408.1};
OS Hahellaceae bacterium.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Hahellaceae.
OX NCBI_TaxID=2048971 {ECO:0000313|EMBL:MAM86408.1, ECO:0000313|Proteomes:UP000225829};
RN [1] {ECO:0000313|Proteomes:UP000225829}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Tully B.J., Graham E.D., Heidelberg J.F.;
RT "The Reconstruction of 2,631 Draft Metagenome-Assembled Genomes from the
RT Global Oceans.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MAM86408.1}.
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DR EMBL; NZNF01000009; MAM86408.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2D8R8U9; -.
DR Proteomes; UP000225829; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 4.
DR CDD; cd12914; PDC1_DGC_like; 1.
DR CDD; cd18774; PDC2_HK_sensor; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 5.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 4.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08448; PAS_4; 3.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00091; PAS; 4.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 4.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 4.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 291..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 311..364
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 394..448
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 523..599
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 602..655
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 656..710
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 780..850
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 934..1067
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 1068 AA; 117752 MW; F3E1289A174CDEF6 CRC64;
MGQQLAALTA GLTLIFTLAL VHFVGGGTLE RARENVGMQL HELAYQTTDK LDRGMFERYR
EMQLLAERLS QPGVSMDQPS LQAVLDVLQE TYPFYAWLGV TDMQGKVVAS TGSILQGADV
SSRPWFSNAL NGIYLADVHD AVLLAQLLPN PTNEPKRFFD VAFPIHDESG EPRGVLGAHL
SWQWAKEVED SVLRTLRASF DSEALILTND GEVLLGPDEL LGKKLLLPSV QRARSGQGGF
TNEEWPDGEP YVVGYSESQG YRNYPGFGWI VLVRQLQDTA FSPVFELQRS LLSGGLIAAL
VFSTLVLLLA RRLTRPLRKI AASAHAIESG RDKTIVTFPG SPREVATLTG ALNGLLKKLA
DKEQQQLELN ANLETRVQQR TTELADMVEA LTESEAHIRA VIDTALDAFI GVDSAGIITD
WNRQAEVMFG WSKAEILGAP VSSSIIPPRF REAHARGMRH FTPASKTGVI GQRLQLFALR
RNGEEFPVEM TIGLIESSRQ YSFGTFIQDI SARKHAEDAL ARERSLLNAV LETIEVGVVA
CNSAGKLVLF NRAARNLHGQ NPQEVPDAEW AREFSLYHAD AETLLQKEEI PLYRALKGEI
VQSAEIAVRA DPDQAPRFLL ASARAMMNDA GDQLGAVVAM QDITALKESA RELARNEERL
RAITENIPAL IGQVDRDERF TFLNSRGAGL FGRTPEALVG ETVANAYGPE RYGKFAPQIA
AARAGKKVVF DDTVRLKDSI RHFQAMYIPQ FDSAGEPDGF YALAFDMTDR KTGELRLAES
EERLRTITDN LPVLIAYIDR EEIYRFANAT YETWFGVSPE QMIGKSVSDI LGPEFYPTVR
EQLQKNLAGE HIRFDAEMRV DGEQRVARLV GIPDVKDDVI RGVYIMTTDI TSERLHEQQL
QSLARQDTLT GLPNRRAFGE AFSAATLRGT RAGTPVVLMI LDVDHFKRIN DSLGHSGGDA
VLTEFARRLK ACVRATDTVA RFAGDEFTII LENVVPPTDA MLVAEKIVQA MRASFDVLGK
KTTVTTSIGI AFAFGTDIEE ATLVARADEA LYEAKAKGRD GYALAQPG
//
