ID   A0A2D8R9E2_9GAMM        Unreviewed;       341 AA.
AC   A0A2D8R9E2;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE            EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN   ORFNames=CME36_04555 {ECO:0000313|EMBL:MAM86569.1};
OS   Hahellaceae bacterium.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Hahellaceae.
OX   NCBI_TaxID=2048971 {ECO:0000313|EMBL:MAM86569.1, ECO:0000313|Proteomes:UP000225829};
RN   [1] {ECO:0000313|Proteomes:UP000225829}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Tully B.J., Graham E.D., Heidelberg J.F.;
RT   "The Reconstruction of 2,631 Draft Metagenome-Assembled Genomes from the
RT   Global Oceans.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:MAM86569.1}.
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DR   EMBL; NZNF01000011; MAM86569.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2D8R9E2; -.
DR   Proteomes; UP000225829; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01949; GGDEF; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR   PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        41..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        69..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        94..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        136..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          198..330
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
SQ   SEQUENCE   341 AA;  37989 MW;  5D0B7C0065056D9E CRC64;
     MHRVKRRLEN NYKLSLIIGL SVFAIAGIGP IILYRFYSGN TFVALVDMVL LLTVTGAAIY
     AWITDNIEPP AMVLALVVSG GLVLMMPKLG TPGLFWYFTL VVFNFGMLRA KWALFLNGTV
     MWLVLYLSEL SSWDELLPFV MSALATFGFT FIIVYRSDMQ RMRLEQTSLT DALTGIANRR
     ALDQELDLVF AHFQRFGIPF GLLMLDLDNF KRVNDTAGHE GGDAALRAFT GLLTESLRKE
     DRLFRYGGEE FVVVLANVEQ TTMKQVAQVL CDLVAEELKS PADHTTPITV SIGASLLQAD
     DDGESWIHRA DKALYAAKAG GRNQVVVYEE IDHMQSRGSD A
//