ID A0A2D8RB84_9GAMM Unreviewed; 915 AA.
AC A0A2D8RB84;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=EAL domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CME36_07990 {ECO:0000313|EMBL:MAM87233.1};
OS Hahellaceae bacterium.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Hahellaceae.
OX NCBI_TaxID=2048971 {ECO:0000313|EMBL:MAM87233.1, ECO:0000313|Proteomes:UP000225829};
RN [1] {ECO:0000313|Proteomes:UP000225829}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Tully B.J., Graham E.D., Heidelberg J.F.;
RT "The Reconstruction of 2,631 Draft Metagenome-Assembled Genomes from the
RT Global Oceans.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MAM87233.1}.
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DR EMBL; NZNF01000021; MAM87233.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2D8RB84; -.
DR Proteomes; UP000225829; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR Gene3D; 2.60.40.2380; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR011623; 7TMR_DISM_rcpt_extracell_dom1.
DR InterPro; IPR011622; 7TMR_DISM_rcpt_extracell_dom2.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF07695; 7TMR-DISM_7TM; 1.
DR Pfam; PF07696; 7TMR-DISMED2; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 235..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..346
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 386..406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 493..645
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 653..907
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 915 AA; 102120 MW; F9B97AFAEDD9E43D CRC64;
MCRLYFLKLT HSSALHRVYV ELDDRGGVVI LTSRTSVTLV FRVLSTLCIL LVPIASASSS
ALNAERFDIS VSETQQSLND HLYYQLHEDQ NGGIDPQTFS DIQQAASEPW RPAGARTLNF
GFESGTLWLR IQLFNSSSRS IERIVSINHP ILDDIEYYRV EDGAIVQRVT TGDHRPLSTR
LINNRFFAFP VALEAGDETT LYFRIRSKSS MQAPMMIAAP NHFYERAQRD TVKHALYFGV
MLAMLFYNLF LFLSLRERVY LYYITFVLAT LFTQVSITGL WAQFFFPELG AIQDHIFRFS
VPTMVLSAGL FTVAFLRLDV HAPRLHKWFM GLAAATVCVF AVALFGEYKT VIFASVAVLF
PTFLSCMLAG PYMWLKGSTL ARYYTIAWAG VLLAILVFTL AVFDVIPRSS WTENSPPLFS
ALEAILLSFA LADRLTQERR QRSESQLALL AEIEHRRAAE AGLFRQALYH HRLQIPNRAF
LESWYQQQAA SRHRYAICLI HFSRFHEVNK TLGHTEADRV LQLLSQRLES QAAALPGVVS
LSPAETRFVC SIEGASFALV LRVPDTQGQG DGLPGPALAA ALDKFVLELS EPCASGQLII
EVGAITGIAL LPDHGQQIDT LLQKAQIAVD ACSRLNTLYT LYSEQINPYS ERRLSLAGDL
RRAIKENLLT LAYQPKITAK SLSIDSVEAL LRWQHPQHGF IGPNEFIPVA EQTGSIHALT
EWVLNEALSS IASLRKQGFH LTVAVNTSAV NLRDRDFPKK VSRALKRFDL LPGVLILEVT
ETAMMSDPER ALDVLHDLHK MTVGLSIDDF GTGYSSLAYI KRLPIQEIKL DRSFVMNLGH
AEGGDHIIVE TSIRMAHALG LKIVAEGVET KDGFDILNSL GCDVLQGYYM SRPVSLDALQ
GLLTETAGIF SHPEA
//
