ID A0A2D8RE76_9GAMM Unreviewed; 335 AA.
AC A0A2D8RE76;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=L-histidine N(Alpha)-methyltransferase {ECO:0000313|EMBL:MAM88263.1};
GN Name=egtD {ECO:0000313|EMBL:MAM88263.1};
GN ORFNames=CME36_13245 {ECO:0000313|EMBL:MAM88263.1};
OS Hahellaceae bacterium.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Hahellaceae.
OX NCBI_TaxID=2048971 {ECO:0000313|EMBL:MAM88263.1, ECO:0000313|Proteomes:UP000225829};
RN [1] {ECO:0000313|Proteomes:UP000225829}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Tully B.J., Graham E.D., Heidelberg J.F.;
RT "The Reconstruction of 2,631 Draft Metagenome-Assembled Genomes from the
RT Global Oceans.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MAM88263.1}.
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DR EMBL; NZNF01000034; MAM88263.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2D8RE76; -.
DR Proteomes; UP000225829; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR035094; EgtD.
DR InterPro; IPR019257; MeTrfase_dom.
DR InterPro; IPR017804; MeTrfase_EgtD-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR03438; egtD_ergothio; 1.
DR PANTHER; PTHR43397; ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1; 1.
DR PANTHER; PTHR43397:SF1; ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1; 1.
DR Pfam; PF10017; Methyltransf_33; 1.
DR PIRSF; PIRSF018005; UCP018005; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:MAM88263.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:MAM88263.1}.
FT DOMAIN 32..333
FT /note="Histidine-specific methyltransferase SAM-dependent"
FT /evidence="ECO:0000259|Pfam:PF10017"
SQ SEQUENCE 335 AA; 37559 MW; EBD9D49AAA920B94 CRC64;
MTDDCVARKV SLQSEPVVTE DYDDPARDAL LADVLDGLSQ AQKRLPSKYF YDRRGSELFE
KICELPEYYP TRTEVAMLDG VAEALKSLLP DVTEIVEFGS GNCTKVEKLL KHMGKVRRYL
PIDVSETFLL HHCQRLDARF PKLDVVPVVG DFTDTVDLAA VEGQTRQPKR LGFFPGSTIG
NLTHEEAIAF LKTAAETLGS GNYLLIGVDT LKSPDVLIPA YDDAQGITAA FNLNLLERLQ
RELGAEIEID NFSHEARFNE EEGRIEMHLV SRCEQTIRVA GKTFNFQAGE SIHTENSHKY
SIEGFCRLAE QAGWRCENSW VADEQLFSIH LLQAS
//
