ID   A0A2D8RG38_9GAMM        Unreviewed;      1773 AA.
AC   A0A2D8RG38;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=DNA helicase {ECO:0000313|EMBL:MAM88927.1};
GN   ORFNames=CME36_16610 {ECO:0000313|EMBL:MAM88927.1};
OS   Hahellaceae bacterium.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Hahellaceae.
OX   NCBI_TaxID=2048971 {ECO:0000313|EMBL:MAM88927.1, ECO:0000313|Proteomes:UP000225829};
RN   [1] {ECO:0000313|Proteomes:UP000225829}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Tully B.J., Graham E.D., Heidelberg J.F.;
RT   "The Reconstruction of 2,631 Draft Metagenome-Assembled Genomes from the
RT   Global Oceans.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:MAM88927.1}.
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DR   EMBL; NZNF01000040; MAM88927.1; -; Genomic_DNA.
DR   Proteomes; UP000225829; Unassembled WGS sequence.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   CDD; cd18808; SF1_C_Upf1; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR045055; DNA2/NAM7-like.
DR   InterPro; IPR041679; DNA2/NAM7-like_C.
DR   InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR   InterPro; IPR025103; DUF4011.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR049468; Restrct_endonuc-II-like_dom.
DR   InterPro; IPR047187; SF1_C_Upf1.
DR   PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR   Pfam; PF13086; AAA_11; 2.
DR   Pfam; PF13087; AAA_12; 1.
DR   Pfam; PF13195; DUF4011; 1.
DR   Pfam; PF18741; MTES_1575; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000313|EMBL:MAM88927.1};
KW   Helicase {ECO:0000313|EMBL:MAM88927.1};
KW   Hydrolase {ECO:0000313|EMBL:MAM88927.1};
KW   Nucleotide-binding {ECO:0000313|EMBL:MAM88927.1}.
FT   DOMAIN          669..746
FT                   /note="DNA2/NAM7 helicase helicase"
FT                   /evidence="ECO:0000259|Pfam:PF13086"
FT   DOMAIN          1228..1360
FT                   /note="DNA2/NAM7 helicase helicase"
FT                   /evidence="ECO:0000259|Pfam:PF13086"
FT   DOMAIN          1391..1611
FT                   /note="DNA2/NAM7 helicase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13087"
FT   DOMAIN          1674..1765
FT                   /note="Restriction endonuclease type II-like"
FT                   /evidence="ECO:0000259|Pfam:PF18741"
FT   REGION          1..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        19..38
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1773 AA;  201396 MW;  F11253CDFC59F361 CRC64;
     MAGYRSPFCR TGYKGTQADE DPLQHHSQTD RGHTRCSERP PGEAAMMPLQ AYLAEQFEQS
     GFTTEDALAA FLPLLAQVLS DHQAGKVAPL EGLQALNVER GSIWYERINH LAPRLQPDRV
     RAIDEARHLA IDVVNRHQLD IDVGGQQQSR QVNVRLANEV ITTPVYVPGY VSWEHQLDHH
     DPLTDIFSLG MILASLCCSL DFNDESDLRR FAASRNNLFA LQPGIHPVVA KTILGMTELS
     RHVRLSDLET IQTMLTNYRQ QTVDFDLEIS QIPGFEAKTL GDRQQIILSK LQERLFEISR
     RNRLYHFKPS MQSLNLTQAS VPLSFNVENI RPDEIMTWTP RLQAQIVREK PIALSSYLNF
     HEVLYLPGSL DKIRTEAAKD QKEYGFAQLR LVLCFLNWSN LKDQDQSQLR SPLVLQPVEL
     QKKKGVRDTW WLKPLSSEAE INPVIRYQFK TLFGVNLPER IDLQETTLDA LYDHLQQQIA
     ASEPGVTLDK IERPRIDLIQ ASAKRRLDQY RKRTRLTGRS ISRYANLDYS YDPANFNPLG
     IRLFNEYVRA PVTDLKRMVS VLPIAQQYAV APSAETVAQN EVTAQRQFYR LRDDDEQNPY
     QWAFDLCNMT LANFKYRKMS LVKDYAELVE NPLANDAFEA TFSLQARELA ATPPAPLPLQ
     ARYHVVPCDP TQTMAIAHAR AGKSYIIQGP PGTGKSQTIT NLIADYIMRD QRVLFVCEKR
     AAIDVVFLRL KQKGLDPLCC LIHDSQADKK SFVMDLKKTY EDFLAAGHGA GADQGPGEAA
     RRRQDTLTAM EEVLAPLQAF SEQTTTVLEQ AGGSLLHLMQ MLIAAPASHP SLDPEQLEQL
     PHYTVWVQNR STIDGFIQRL APLQPSQVFS EHPLRLLNPI LADHDSPLGL LRTTVPDVLQ
     NLRMLLSGLT SLGLPAGSWD TLDHIEAMLV IARQLEPLSR WGLLGLLDEH SQQFSEYQKL
     QRQKKKRMLE LVDKHEQNKH WNSRLSAEDT GIALAQATRL DSVFRFFFPS YWKLRSLLKH
     SYDFAAHAIA PSWIHVLQQL TQEHEARKAL QSIESEAQES LGFDVSLQAF EGHVVEAQRI
     MATLDGPVQA LRPTLQDPKQ AASLISQLLS LELPLSNLRQ GLGHILVDYQ DLNVEDLQAE
     LLQMEGALQH NVSEFLFALK PLRELPEQLT RNFRHQPWSI EQLELMSAER SLSQALNSNR
     SLREHDGSKR RHYIDRLRTL YQQWQHHNSA AILETVRNKF LEHVRISAAP AAQLTQAQKD
     FKKVYAKGRR ELEHEFSKSM RYKPIRDMVA FESGAVIRDL KPVWLMSPLS VSDTLPLNSR
     TFDVIIFDEA SQITLEGAIP SLFRAPQTIV VGDQMQLPPT NFFSTRTDTE DEVMVTTDEG
     EQVEYDLSSN SFLNHVAKNL KSYMLGWHYR SRSEHLISFS NWAFYQGQLL TVPDEKTVPR
     VQAPMTISSA ADAGHHIQHL LSRPVSFHHM PENVYDQRRN TGEAEYIAQL VRHLLAQDKP
     RSVGIIAFSE AQQDEIESAL DRLAAEDSEF ALRYEQEQER EEDGEFVGLL VKNLENIQGD
     ERDIIIMSIC YGYGKDRKMR MNFGPINQSG GEKRLNVAFS RAKHHMVVVS SIQSVDITND
     YNEGANSLKN YLRYSQALSA GDIASANQVL MDIGLTAQRS RPAAPPPSAV SSQLKSELEA
     RGWQVDIAVG QSHFKCDLGV KRPGDDRYAL GILIDSEQFY AQSDLLEREF HKPELLKNFG
     WQIEFVLTKD WLMNRDRVLA TLTDAMGAPP HKT
//