ID A0A2D8RG80_9GAMM Unreviewed; 833 AA.
AC A0A2D8RG80;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=CME36_16535 {ECO:0000313|EMBL:MAM88912.1};
OS Hahellaceae bacterium.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Hahellaceae.
OX NCBI_TaxID=2048971 {ECO:0000313|EMBL:MAM88912.1, ECO:0000313|Proteomes:UP000225829};
RN [1] {ECO:0000313|Proteomes:UP000225829}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Tully B.J., Graham E.D., Heidelberg J.F.;
RT "The Reconstruction of 2,631 Draft Metagenome-Assembled Genomes from the
RT Global Oceans.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MAM88912.1}.
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DR EMBL; NZNF01000040; MAM88912.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2D8RG80; -.
DR Proteomes; UP000225829; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 2.60.40.2380; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR011623; 7TMR_DISM_rcpt_extracell_dom1.
DR InterPro; IPR011622; 7TMR_DISM_rcpt_extracell_dom2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43047:SF9; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF07695; 7TMR-DISM_7TM; 1.
DR Pfam; PF07696; 7TMR-DISMED2; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 187..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 251..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 341..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 478..695
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 720..831
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT COILED 430..468
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 770
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 833 AA; 92833 MW; 1ABA20AA8610E801 CRC64;
MLRLTLSCNR ISWIALFWLC SGLLFASEDL VLNEEASPGN LAASFVYISD RTVASRKQAL
ALPPDRWQKL EHDIFNEGFV GSGFWLKATI RSDVSLEQGN WLLVLNNVLM EELSVYWQHD
SEGLLLELVD FEAGQFAKLP LQGRHWLVPL TIQPGQSYTL LVHMKSFVVS QMPASILPVE
RYLEHELLVG SLLNMAVAAL LVIAVVGLLL ALVYRDIGLF YHSVFVLGVA ILHASLQGLI
FHWLWPHWPW LHKNIAFLAI VVALWAGVMF TREQMSSPES HPMFPKLLYF FAWLQPAVAL
TSLLLPLHLR WQVNVLYLLS SVVTALVMGF VNSLRGQRVA IYYTAAMTIF FIGTFLLALN
KLGFIPVNVY TDNLQLVGSL VGSVIFLLSV NERVNQKRLA KRAVKQQALD YERVAHETQV
QLLRIERQTS EGLEQQVHAR TAELERALQE LKTAHSDLQL AKAAEEKAHL EKTRFLAAAS
HDIRQPLHAL TLLVEDLLLS TPAQTAETVR TGLRVREAVD SLSALFDALF DLSKLDNKLV
RPELELIDLA QLVSDYGERI QPLCQHANTV LQVDIPEKAV MVMSDRLMLE RILTILIDNA
VNHSGSNRIG LVVSVSPSQL RLSVIDHGIG IAENDQVHIF EEFYQVDNEQ RNRSRGMGLG
LALCRRLVGL IGCEITLHSA RGQGARFDIL MSRSPKDTAT ESSGRKAEGA QPTLCLQDKL
VLVVDDDVLA REASAQLLQR WGMSVLPAAD GTEALAVLGE ARAPEFALLD YRLPGSNGLE
LAKAIRARLG SKFPIIILTG DLRLSISEPD IRVLSKPIRP MRLRAAIQAI LQA
//
