ID   A0A2E7NZE3_9BURK        Unreviewed;       328 AA.
AC   A0A2E7NZE3;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=3-phosphoglycerate dehydrogenase {ECO:0000313|EMBL:MBO14846.1};
GN   ORFNames=CME87_05105 {ECO:0000313|EMBL:MBO14846.1};
OS   Herbaspirillum sp.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Oxalobacteraceae; Herbaspirillum.
OX   NCBI_TaxID=1890675 {ECO:0000313|EMBL:MBO14846.1, ECO:0000313|Proteomes:UP000226028};
RN   [1] {ECO:0000313|Proteomes:UP000226028}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Tully B.J., Graham E.D., Heidelberg J.F.;
RT   "The Reconstruction of 2,631 Draft Metagenome-Assembled Genomes from the
RT   Global Oceans.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC       dehydrogenase family. {ECO:0000256|ARBA:ARBA00005854,
CC       ECO:0000256|RuleBase:RU003719}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:MBO14846.1}.
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DR   EMBL; PBPP01000032; MBO14846.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2E7NZE3; -.
DR   Proteomes; UP000226028; Unassembled WGS sequence.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   CDD; cd12169; PGDH_like_1; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR   InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR42789; D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10090); 1.
DR   PANTHER; PTHR42789:SF1; D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10090); 1.
DR   Pfam; PF00389; 2-Hacid_dh; 1.
DR   Pfam; PF02826; 2-Hacid_dh_C; 1.
DR   SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   NAD {ECO:0000256|ARBA:ARBA00023027};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU003719}.
FT   DOMAIN          11..323
FT                   /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT                   catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00389"
FT   DOMAIN          111..292
FT                   /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT                   binding"
FT                   /evidence="ECO:0000259|Pfam:PF02826"
SQ   SEQUENCE   328 AA;  35397 MW;  9EB69A36A2E0F645 CRC64;
     MKIAILDDYQ DAVRHLDCFR LLDGHDVKVF TNTVRGTGQL AARLAPFDAV VLIRERTALT
     QPLLEKLPLL KLISQTGKVS GHVDVAAATA RGIAIVEGVG DPTAPAELTW ALIMAAMRRV
     PQYCSALRAG AWQQVSPTPH HNLIGTALKG RTLGIWGYGK IGKLVAGYGR AFGMQVVVWG
     REASREQAVK DGLQAAASKE DFFTQADVLT LHLRLNDATR GIVKASDLAR MKPTACFVNT
     SRAELVEADA LEAALHAGRP GLAALDVYER EPLPVDSPLL KMDNVVAAPH LGYVEKDGYE
     LYFRAAFQNI VDYAAGTPKN VLNPEALG
//