ID A0A2E9CF76_9ARCH Unreviewed; 155 AA.
AC A0A2E9CF76;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Serine hydroxymethyltransferase {ECO:0000313|EMBL:MBS85737.1};
DE EC=2.1.2.1 {ECO:0000313|EMBL:MBS85737.1};
DE Flags: Fragment;
GN ORFNames=CME83_04200 {ECO:0000313|EMBL:MBS85737.1};
OS Candidatus Heimdallarchaeota archaeon.
OC Archaea; Asgard group; Candidatus Heimdallarchaeota.
OX NCBI_TaxID=2026747 {ECO:0000313|EMBL:MBS85737.1, ECO:0000313|Proteomes:UP000228988};
RN [1] {ECO:0000313|Proteomes:UP000228988}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Tully B.J., Graham E.D., Heidelberg J.F.;
RT "The Reconstruction of 2,631 Draft Metagenome-Assembled Genomes from the
RT Global Oceans.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MBS85737.1}.
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DR EMBL; PBWW01000036; MBS85737.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2E9CF76; -.
DR Proteomes; UP000228988; Unassembled WGS sequence.
DR GO; GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019264; P:glycine biosynthetic process from serine; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0035999; P:tetrahydrofolate interconversion; IEA:InterPro.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR InterPro; IPR001085; Ser_HO-MeTrfase.
DR InterPro; IPR039429; SHMT-like_dom.
DR PANTHER; PTHR11680; SERINE HYDROXYMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR11680:SF28; SERINE HYDROXYMETHYLTRANSFERASE; 1.
DR Pfam; PF00464; SHMT; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:MBS85737.1};
KW Transferase {ECO:0000313|EMBL:MBS85737.1}.
FT DOMAIN 1..119
FT /note="Serine hydroxymethyltransferase-like"
FT /evidence="ECO:0000259|Pfam:PF00464"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:MBS85737.1"
SQ SEQUENCE 155 AA; 17065 MW; 09228EAC820EA3C2 CRC64;
VIAAKAVAFK EALDPSFKNY AKNIIENSKS LATSLVENGA KISTDGTDNH LVLMDISMYD
IGGKIAEHTL DQVGIFTNKN MIPFDKRSPF DPSGIRIGTP ALTTRGLNTS DMEFIGELIV
NALQNYNNNE KLNSIKSQVQ ELSNKYPLYP ELKIS
//
