ID A0A2G0QF78_9GAMM Unreviewed; 79 AA.
AC A0A2G0QF78;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Probable [Fe-S]-dependent transcriptional repressor {ECO:0000256|HAMAP-Rule:MF_01586};
GN Name=feoC {ECO:0000256|HAMAP-Rule:MF_01586};
GN ORFNames=Xhom_00886 {ECO:0000313|EMBL:PHM57883.1};
OS Xenorhabdus hominickii.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=351679 {ECO:0000313|EMBL:PHM57883.1, ECO:0000313|Proteomes:UP000225433};
RN [1] {ECO:0000313|EMBL:PHM57883.1, ECO:0000313|Proteomes:UP000225433}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17903 {ECO:0000313|EMBL:PHM57883.1,
RC ECO:0000313|Proteomes:UP000225433};
RX PubMed=28993611; DOI=10.1038/s41564-017-0039-9;
RA Tobias N.J., Wolff H., Djahanschiri B., Grundmann F., Kronenwerth M.,
RA Shi Y.M., Simonyi S., Grun P., Shapiro-Ilan D., Pidot S.J., Stinear T.P.,
RA Ebersberger I., Bode H.B.;
RT "Natural product diversity associated with the nematode symbionts
RT Photorhabdus and Xenorhabdus.";
RL Nat. Microbiol. 2:1676-1685(2017).
CC -!- FUNCTION: May function as a transcriptional regulator that controls
CC feoABC expression. {ECO:0000256|HAMAP-Rule:MF_01586}.
CC -!- SIMILARITY: Belongs to the FeoC family. {ECO:0000256|HAMAP-
CC Rule:MF_01586}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHM57883.1}.
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DR EMBL; NJAI01000001; PHM57883.1; -; Genomic_DNA.
DR RefSeq; WP_069317559.1; NZ_NJAI01000001.1.
DR AlphaFoldDB; A0A2G0QF78; -.
DR STRING; 351679.A9255_15885; -.
DR KEGG; xho:A9255_15885; -.
DR OrthoDB; 6903254at2; -.
DR Proteomes; UP000225433; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR HAMAP; MF_01586; FeoC; 1.
DR InterPro; IPR023732; FeoC.
DR InterPro; IPR015102; Tscrpt_reg_HTH_FeoC.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF09012; FeoC; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|HAMAP-Rule:MF_01586};
KW Iron {ECO:0000256|HAMAP-Rule:MF_01586};
KW Iron-sulfur {ECO:0000256|HAMAP-Rule:MF_01586};
KW Metal-binding {ECO:0000256|HAMAP-Rule:MF_01586};
KW Repressor {ECO:0000256|HAMAP-Rule:MF_01586};
KW Transcription {ECO:0000256|HAMAP-Rule:MF_01586};
KW Transcription regulation {ECO:0000256|HAMAP-Rule:MF_01586}.
FT DOMAIN 4..68
FT /note="Transcriptional regulator HTH-type FeoC"
FT /evidence="ECO:0000259|Pfam:PF09012"
FT BINDING 54
FT /ligand="iron-sulfur cluster"
FT /ligand_id="ChEBI:CHEBI:30408"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01586"
FT BINDING 59
FT /ligand="iron-sulfur cluster"
FT /ligand_id="ChEBI:CHEBI:30408"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01586"
FT BINDING 62
FT /ligand="iron-sulfur cluster"
FT /ligand_id="ChEBI:CHEBI:30408"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01586"
FT BINDING 68
FT /ligand="iron-sulfur cluster"
FT /ligand_id="ChEBI:CHEBI:30408"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01586"
SQ SEQUENCE 79 AA; 8588 MW; EF863656C97735DF CRC64;
MISLLEIRDA VALNGRTDAR TLSHQFSAPL PMVEAMLQQL VMMGKLEEVD ASSCLSGGCK
QCPETQKCDT KAYQLAVKS
//
