ID A0A2G1X0H5_9EURY Unreviewed; 478 AA.
AC A0A2G1X0H5;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Multidrug-efflux transporter {ECO:0000256|ARBA:ARBA00031636};
GN ORFNames=DJ68_16860 {ECO:0000313|EMBL:PHQ44735.1};
OS Halorubrum sp. C3.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Halorubraceae; Halorubrum.
OX NCBI_TaxID=1483399 {ECO:0000313|EMBL:PHQ44735.1, ECO:0000313|Proteomes:UP000225238};
RN [1] {ECO:0000313|EMBL:PHQ44735.1, ECO:0000313|Proteomes:UP000225238}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C3 {ECO:0000313|EMBL:PHQ44735.1,
RC ECO:0000313|Proteomes:UP000225238};
RX PubMed=24782836; DOI=10.3389/fmicb.2014.00140;
RA Fullmer M.S., Soucy S.M., Swithers K.S., Makkay A.M., Wheeler R.,
RA Ventosa A., Gogarten J.P., Papke R.T.;
RT "Population and genomic analysis of the genus Halorubrum.";
RL Front. Microbiol. 5:140-140(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHQ44735.1}.
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DR EMBL; NHOB01001015; PHQ44735.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G1X0H5; -.
DR Proteomes; UP000225238; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR CDD; cd13137; MATE_NorM_like; 1.
DR InterPro; IPR002528; MATE_fam.
DR InterPro; IPR048279; MdtK-like.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR43298:SF2; FMN_FAD EXPORTER YEEO-RELATED; 1.
DR PANTHER; PTHR43298; MULTIDRUG RESISTANCE PROTEIN NORM-RELATED; 1.
DR Pfam; PF01554; MatE; 2.
DR PIRSF; PIRSF006603; DinF; 1.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 38..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 171..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 320..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 422..443
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 456..478
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 478 AA; 49158 MW; B66785E33A1B90DD CRC64;
MDFPRLRRVW KRVFSLAWPV MAEQTFRTAM RTTDILVTAL FSPAAVVAIG LADLYARFPL
RIGLGLGGGA IALSSQDTGA GAAENRDEAV TQAILLGALA GVPFVLFGFL FGELAIDVFG
RLVGERTSPA VVDLGSTYLA IVFATAPARH VALVGARALQ GTGDTRTPMY VNIAANSVNI
AGSVVLGLGL FGLPRLEVVG VGLATAGANV LTAGLLCFAI WGSWTDADFA RPRDLTVAKQ
LLVVSAPRVL EGFGSEIAEF PFNALLLGFG ETVNAGFQIG RRVYQQVTGP LSRGYNVAAS
ILVGQALGEG DPEGARFNGW AVASLGVLTV GAIGLGLVVA APRIVPVFTD DAATVASAVD
FARVYGVAGA ALACFSALSG SLQGASETRI PLVARVSGMF GLFLGLSWLL GRTAGFGPEG
AYVGVFAAYA WMALVVAAGF RYTDWASRAA DMMDARGSGP GAESDAASGD GSPADDSP
//
