ID A0A2G1X2C1_9EURY Unreviewed; 550 AA.
AC A0A2G1X2C1;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=NADH dehydrogenase subunit D {ECO:0000313|EMBL:PHQ45374.1};
GN ORFNames=DJ68_13235 {ECO:0000313|EMBL:PHQ45374.1};
OS Halorubrum sp. C3.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Halorubraceae; Halorubrum.
OX NCBI_TaxID=1483399 {ECO:0000313|EMBL:PHQ45374.1, ECO:0000313|Proteomes:UP000225238};
RN [1] {ECO:0000313|EMBL:PHQ45374.1, ECO:0000313|Proteomes:UP000225238}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C3 {ECO:0000313|EMBL:PHQ45374.1,
RC ECO:0000313|Proteomes:UP000225238};
RX PubMed=24782836; DOI=10.3389/fmicb.2014.00140;
RA Fullmer M.S., Soucy S.M., Swithers K.S., Makkay A.M., Wheeler R.,
RA Ventosa A., Gogarten J.P., Papke R.T.;
RT "Population and genomic analysis of the genus Halorubrum.";
RL Front. Microbiol. 5:140-140(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) +
CC NAD(+); Xref=Rhea:RHEA:57888, ChEBI:CHEBI:15378, ChEBI:CHEBI:24646,
CC ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:132124;
CC Evidence={ECO:0000256|ARBA:ARBA00000100};
CC -!- SUBUNIT: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD,
CC E, F, and G constitute the peripheral sector of the complex.
CC {ECO:0000256|ARBA:ARBA00038617}.
CC -!- SIMILARITY: In the C-terminal section; belongs to the complex I 49 kDa
CC subunit family. {ECO:0000256|ARBA:ARBA00010019}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHQ45374.1}.
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DR EMBL; NHOB01000799; PHQ45374.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G1X2C1; -.
DR Proteomes; UP000225238; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR Gene3D; 1.10.645.10; Cytochrome-c3 Hydrogenase, chain B; 1.
DR Gene3D; 3.30.460.80; NADH:ubiquinone oxidoreductase, 30kDa subunit; 1.
DR HAMAP; MF_01358; NDH1_NuoD; 1.
DR InterPro; IPR001135; NADH_Q_OxRdtase_suD.
DR InterPro; IPR037232; NADH_quin_OxRdtase_su_C/D-like.
DR InterPro; IPR001268; NADH_UbQ_OxRdtase_30kDa_su.
DR InterPro; IPR020396; NADH_UbQ_OxRdtase_CS.
DR InterPro; IPR022885; NDH1_su_D/H.
DR InterPro; IPR029014; NiFe-Hase_large.
DR PANTHER; PTHR11993:SF10; NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11993; NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT; 1.
DR Pfam; PF00329; Complex1_30kDa; 1.
DR Pfam; PF00346; Complex1_49kDa; 1.
DR SUPFAM; SSF56762; HydB/Nqo4-like; 1.
DR SUPFAM; SSF143243; Nqo5-like; 1.
DR PROSITE; PS00542; COMPLEX1_30K; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00022475};
KW Multifunctional enzyme {ECO:0000256|ARBA:ARBA00023268}.
FT DOMAIN 38..154
FT /note="NADH:ubiquinone oxidoreductase 30kDa subunit"
FT /evidence="ECO:0000259|Pfam:PF00329"
FT DOMAIN 300..550
FT /note="NADH-quinone oxidoreductase subunit D"
FT /evidence="ECO:0000259|Pfam:PF00346"
SQ SEQUENCE 550 AA; 62161 MW; 5B2B0DDC37ED64CA CRC64;
MSTEVLRDRD DEEAADPFSS IRELVTAHED HLNAPAARVR PDSVQEALTA LRDEAGYDHL
ACVTAQEYEG RYESIYHLRS YDDPTREVSV VVPADKGDPV SESAAPVFRT ADWHEREAYD
LVGIEYDDHP DLRRILLPET WQGHPLSMDY DKDQPQIAAL SENEPIEPGS STATGSDTML
LNIGPHHPAT HGVLHLQVTL DGEQVIGVEP DIGYIHRCEE QMAQSGTYRH QIMPYPDRWD
WGGGGLLNEW AYARVAEDLA DIEVPEYAQV IRTMAAEFSR VLSHMLAMGA YALDVIGDFT
ATFMYAIQER ERVQDIVEDL TGQRLMFNYF RLGGVAWDLP EPREEFLRSV REYLDGLPRR
IEEYHDLLTR NEILQLRTVD TGVLPPEVAK EYGTTGPVLR GSGVDYDLRR DDPYGYYDEL
DWDVVTEDGC DNYSRLLVRM REVEESAKII EQCVDLLEGW PEDERTVQAN VPRTIRPDND
TEVYRAVEAA KGELGIYIRA DGTDEPARFK IRGPSFSNLQ ALPEMAEGEA IPDLIASLGS
LDTIMGEVDR
//
