ID   A0A2G1XGS4_STRCJ        Unreviewed;       331 AA.
AC   A0A2G1XGS4;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:PHQ50433.1};
DE   SubName: Full=WYL domain-containing protein {ECO:0000313|EMBL:PPT12878.1};
GN   ORFNames=BLA24_22585 {ECO:0000313|EMBL:PHQ50433.1}, CYQ11_08205
GN   {ECO:0000313|EMBL:PPT12878.1};
OS   Streptomyces cinnamoneus (Streptoverticillium cinnamoneum).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces; Streptomyces cinnamoneus group.
OX   NCBI_TaxID=53446 {ECO:0000313|EMBL:PHQ50433.1, ECO:0000313|Proteomes:UP000222531};
RN   [1] {ECO:0000313|EMBL:PHQ50433.1, ECO:0000313|Proteomes:UP000222531}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 21532 {ECO:0000313|EMBL:PHQ50433.1,
RC   ECO:0000313|Proteomes:UP000222531};
RX   PubMed=29053243;
RA   Patteson J., Cai W., Johnson R.A., Santa Maria K., Li B.;
RT   "Identification of the Biosynthetic Pathway for the Antibiotic
RT   Bicyclomycin.";
RL   Biochemistry 0:0-0(2017).
RN   [2] {ECO:0000313|EMBL:PPT12878.1, ECO:0000313|Proteomes:UP000239771}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 41675 {ECO:0000313|EMBL:PPT12878.1,
RC   ECO:0000313|Proteomes:UP000239771};
RA   Vior N.M., Lacret R., Chandra G., Dorai-Raj S., Trick M., Truman A.W.;
RT   "Discovery and biosynthesis of the antibiotic bicyclomycin in distant
RT   bacterial classes.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PHQ50433.1}.
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DR   EMBL; NHZO01000151; PHQ50433.1; -; Genomic_DNA.
DR   EMBL; PKFQ01000001; PPT12878.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G1XGS4; -.
DR   OrthoDB; 3171994at2; -.
DR   Proteomes; UP000222531; Unassembled WGS sequence.
DR   Proteomes; UP000239771; Unassembled WGS sequence.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR013196; HTH_11.
DR   InterPro; IPR028349; PafC.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   InterPro; IPR026881; WYL_dom.
DR   PANTHER; PTHR34580; -; 1.
DR   PANTHER; PTHR34580:SF6; HTH DEOR-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF08279; HTH_11; 1.
DR   Pfam; PF13280; WYL; 1.
DR   PIRSF; PIRSF016838; PafC; 2.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000222531}.
FT   DOMAIN          5..60
FT                   /note="Helix-turn-helix type 11"
FT                   /evidence="ECO:0000259|Pfam:PF08279"
FT   DOMAIN          140..318
FT                   /note="WYL"
FT                   /evidence="ECO:0000259|Pfam:PF13280"
SQ   SEQUENCE   331 AA;  36351 MW;  3D28B0A0682AA513 CRC64;
     MRAARLIKLV LLLQSRASTT GPELARRLEV SERTVARDVL ALSEAGVPVY ADRGRAGGYR
     LVGGYRTRLT GLDRTEAEAL FLSGVPSALR EMGLADVASA ARLKVSAALL PELSDAPASA
     AQRFHLDAPA WWQSADPPPL LPAVARAVWD DLRLTARYRR RETEAERVLE PYGLVLKGGV
     WYLAARVPEG AFRVYRLDRF VAATAGEEHF DREESFDLPE FWEERAAEFA RSILRETVGL
     RLTPEGARRL PHVTDRAEAR RALAAAPGPD ARQRVTVTLA VETLEVAYDQ LLALGPEAEV
     LDPPELRDRF ARAAARAAAL YDRDASGEPS P
//