ID A0A2G1XMM9_STRCJ Unreviewed; 360 AA.
AC A0A2G1XMM9;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Geranylgeranyl diphosphate synthase {ECO:0000313|EMBL:PPT15995.1};
GN ORFNames=BLA24_06675 {ECO:0000313|EMBL:PHQ52463.1}, CYQ11_26825
GN {ECO:0000313|EMBL:PPT15995.1};
OS Streptomyces cinnamoneus (Streptoverticillium cinnamoneum).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces cinnamoneus group.
OX NCBI_TaxID=53446 {ECO:0000313|EMBL:PHQ52463.1, ECO:0000313|Proteomes:UP000222531};
RN [1] {ECO:0000313|EMBL:PHQ52463.1, ECO:0000313|Proteomes:UP000222531}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 21532 {ECO:0000313|EMBL:PHQ52463.1,
RC ECO:0000313|Proteomes:UP000222531};
RX PubMed=29053243;
RA Patteson J., Cai W., Johnson R.A., Santa Maria K., Li B.;
RT "Identification of the Biosynthetic Pathway for the Antibiotic
RT Bicyclomycin.";
RL Biochemistry 0:0-0(2017).
RN [2] {ECO:0000313|EMBL:PPT15995.1, ECO:0000313|Proteomes:UP000239771}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 41675 {ECO:0000313|EMBL:PPT15995.1,
RC ECO:0000313|Proteomes:UP000239771};
RA Vior N.M., Lacret R., Chandra G., Dorai-Raj S., Trick M., Truman A.W.;
RT "Discovery and biosynthesis of the antibiotic bicyclomycin in distant
RT bacterial classes.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHQ52463.1}.
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DR EMBL; NHZO01000081; PHQ52463.1; -; Genomic_DNA.
DR EMBL; PKFQ01000001; PPT15995.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G1XMM9; -.
DR OrthoDB; 4497239at2; -.
DR Proteomes; UP000222531; Unassembled WGS sequence.
DR Proteomes; UP000239771; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR12001:SF88; (2E,6E)-FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000222531};
KW Transferase {ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 360 AA; 38276 MW; 76A7995DB8BE5C92 CRC64;
MTILETATPH IDLGRVRQAV EDTLECFLAG KAEGEDGARI AAPLRVLRDF LGGGGKRVRP
LYCCLGWFAV AGRPPTTEVL RAAAGLELFH TFALIHDDVI DGSDSRHARP TAHRAFEQDG
PGPRARWFGE SAAILLGDLC EVWSAELLGG LSGPSPASAR AVLDRMRGEL VIGQFLDLRA
FGTDFGNVED ALAVIHYKTT KYTVERPLQI GAAMAGASSS VLGVCAAYAR PMGEAFQMCD
DLEDVLPDPA RGDATGNDLR EGKHTVVLAL ALRDAGAAES ARLRELVGDP DLDADGLAEA
QALIAATGAP RTVRRMVVER RRQALDVLAA APFGPAARQA LARLTDLALP GVDRWEEAEG
//
