ID   A0A2G1ZYZ3_9COXI        Unreviewed;       309 AA.
AC   A0A2G1ZYZ3;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   RecName: Full=HTH lysR-type domain-containing protein {ECO:0000259|PROSITE:PS50931};
GN   ORFNames=COB66_03380 {ECO:0000313|EMBL:PHQ80997.1};
OS   Coxiella sp. (in: g-proteobacteria).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales; Coxiellaceae;
OC   Coxiella.
OX   NCBI_TaxID=59288 {ECO:0000313|EMBL:PHQ80997.1, ECO:0000313|Proteomes:UP000225126};
RN   [1] {ECO:0000313|Proteomes:UP000225126}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Tully B.J., Wheat C.G., Glazer B.T., Huber J.A.;
RT   "A dynamic microbial community with high functional redundancy inhabits the
RT   cold, oxic subseafloor aquifer.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000256|ARBA:ARBA00009437}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PHQ80997.1}.
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DR   EMBL; NVSS01000042; PHQ80997.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G1ZYZ3; -.
DR   Proteomes; UP000225126; Unassembled WGS sequence.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd08422; PBP2_CrgA_like; 1.
DR   Gene3D; 3.40.190.290; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30537; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
FT   DOMAIN          3..60
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50931"
SQ   SEQUENCE   309 AA;  35671 MW;  6736AF56E03E72DF CRC64;
     MRPDIEHIMT YIKVVELGSF TSAAHDMNLS KSVVSKHVSS LEESLNTRLL KRTTRKLSVT
     DVGKVFYEQV KNIPYEVENA QQAIQPFNDE PHGLLKVISP ANFIASLKTD VVPDYLLKYP
     KVNLSLRGVR PVVDHINDEY DIIILWKLEH LNFQDYNMVA VKLFSMPVGI YVTPEYLEKN
     GTPRTPDDLA AHNCFSSIGR RWPFCEKNGS VYYKAVDGRL RSQNDEITQS ACRKSVGITY
     SYPFLFEEDL ADGTVVQILR DYTQLNIEMY AFYHPTSFLP PKISHFIDEL KEFYRERQEE
     ILRCGRDAE
//