ID A0A2G2W6U7_CAPBA Unreviewed; 1067 AA.
AC A0A2G2W6U7;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Bifunctional fucokinase/fucose pyrophosphorylase {ECO:0000313|EMBL:PHT40942.1};
GN ORFNames=CQW23_19796 {ECO:0000313|EMBL:PHT40942.1};
OS Capsicum baccatum (Peruvian pepper).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Capsiceae; Capsicum.
OX NCBI_TaxID=33114 {ECO:0000313|EMBL:PHT40942.1, ECO:0000313|Proteomes:UP000224567};
RN [1] {ECO:0000313|EMBL:PHT40942.1, ECO:0000313|Proteomes:UP000224567}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. PBC81 {ECO:0000313|Proteomes:UP000224567};
RC TISSUE=Leaf {ECO:0000313|EMBL:PHT40942.1};
RX PubMed=29089032; DOI=10.1186/s13059-017-1341-9;
RA Kim S., Park J., Yeom S.I., Kim Y.M., Seo E., Kim K.T., Kim M.S., Lee J.M.,
RA Cheong K., Shin H.S., Kim S.B., Han K., Lee J., Park M., Lee H.A.,
RA Lee H.Y., Lee Y., Oh S., Lee J.H., Choi E., Choi E., Lee S.E., Jeon J.,
RA Kim H., Choi G., Song H., Lee J., Lee S.C., Kwon J.K., Lee H.Y., Koo N.,
RA Hong Y., Kim R.W., Kang W.H., Huh J.H., Kang B.C., Yang T.J., Lee Y.H.,
RA Bennetzen J.L., Choi D.;
RT "New reference genome sequences of hot pepper reveal the massive evolution
RT of plant disease-resistance genes by retroduplication.";
RL Genome Biol. 18:R210.1-R210.11(2017).
RN [2] {ECO:0000313|Proteomes:UP000224567}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. PBC81 {ECO:0000313|Proteomes:UP000224567};
RA Kim S., Park J., Yeom S.-I., Kim Y.-M., Seo E., Kim K.-T., Kim M.-S.,
RA Lee J.M., Cheong K., Shin H.-S., Kim S.-B., Han K., Lee J., Park M.,
RA Lee H.-A., Lee H.-Y., Lee Y., Oh S., Lee J.H., Choi E., Choi E., Lee S.E.,
RA Jeon J., Kim H., Choi G., Song H., Lee J., Lee S.-C., Kwon J.-K.,
RA Lee H.-Y., Koo N., Hong Y., Kim R.W., Kang W.-H., Huh J.H., Kang B.-C.,
RA Yang T.-J., Lee Y.-H., Bennetzen J.L., Choi D.;
RT "Multiple reference genome sequences of hot pepper reveal the massive
RT evolution of plant disease resistance genes by retroduplication.";
RL J. Anim. Genet. bioRxivorg:115410-115410(2017).
CC -!- SIMILARITY: Belongs to the GHMP kinase family.
CC {ECO:0000256|ARBA:ARBA00038121}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHT40942.1}.
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DR EMBL; MLFT02000008; PHT40942.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G2W6U7; -.
DR STRING; 33114.A0A2G2W6U7; -.
DR Proteomes; UP000224567; Chromosome 8.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR Gene3D; 3.30.230.120; -; 1.
DR InterPro; IPR012887; Fucokinase.
DR InterPro; IPR013750; GHMP_kinase_C_dom.
DR InterPro; IPR036554; GHMP_kinase_C_sf.
DR InterPro; IPR006204; GHMP_kinase_N_dom.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR PANTHER; PTHR32463; L-FUCOSE KINASE; 1.
DR PANTHER; PTHR32463:SF0; L-FUCOSE KINASE; 1.
DR Pfam; PF07959; Fucokinase; 1.
DR Pfam; PF08544; GHMP_kinases_C; 1.
DR Pfam; PF00288; GHMP_kinases_N; 1.
DR PRINTS; PR00959; MEVGALKINASE.
DR SUPFAM; SSF55060; GHMP Kinase, C-terminal domain; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000313|EMBL:PHT40942.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000224567};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 137..534
FT /note="L-fucokinase"
FT /evidence="ECO:0000259|Pfam:PF07959"
FT DOMAIN 828..895
FT /note="GHMP kinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00288"
FT DOMAIN 972..1049
FT /note="GHMP kinase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08544"
SQ SEQUENCE 1067 AA; 117295 MW; 8BA808899760C422 CRC64;
MERKYNIRSR GKADLAGILR KSWYHLRLSV RHPARVPTWD AIVLTAASPE QAQLYEWQLK
RAKRMGRIAD STITLAVPDP DGQRIGSGAA TLHAILELAK HYQQISLDSQ CGSSQMKEPS
SSYIYLIAKK HILLLHAGGD SKRVPWANPM GKVFLPLPYL AADDQDGPVP LLFDHILAIA
SCARQAFENE GGMLTMTGDV LPCFDASIMV LPKDASCIVT VPITLDIASN HGVIVAAKSG
ISNDTYSLNL VENLLQKPCL DELVRHQAIL DDGRTLLDTG IIAVRGQAWL NLVKLACSSQ
SMISELLEKK KEMSLYEDLV AAWVPAKNEW LRSRPLGDEL VNKLGEQEMF SYCAYDLLFL
HFGTSSEVLD HMSETGAGLV GRRHLSSIPA TNVSDIAASA IILSSKIEPG VSIGEDSLIY
DSFISGGIQI GSQSIVVGTH VPAASDMTEK VPFRFMLPDR HCFWEVPLVE RTERVIVYCG
IHDNPKILLS NGTFCGKPWR KVLDDLGIQD TDLWTSEKTR EKCLWNAKIF PVLPYFEMLT
LASWLMGLDN QRNETLCSSW KRSQRISLEE LHRSINFSQI CLGSSNHQAD LASGIVNACL
NFGLLGRNLS QLFQEILQKE STGIEVCKGF LSHCPKLQAQ NSAILPKSRA YQVHADLLRA
CGNEEMALEA QQKVWASVAD ETASAVRYGF KENLAGSSSW FSITANPGNT NGCCGESFHH
KTVKIELPVR VDFVGGWSDT PPWSLERAGC VLNMAITLEN SLPVGTVIET EKGTGIFVSD
DVGNQLSIED LSSISLPFET SDPFRLVKSA LLVTNVIHAK ILQSVGLRIR TWANVPRGSG
LGTSSILAAA VVKGLLRITD GDESNENVAR LVLVLEQLMG TGGGWQDQIG GLYAGIKFTT
SFPGIPLRLQ VIPLLASSQL IKELQQRLLV VFTGQVRLAH QVLHKVVTRY LQRDNLLVSS
IKRLAELAKI AREALMNCDI DALGDIMLEA WRLHQELDPF CSNEFVDKLF AFCDRYCCGY
KLVGAGGGGF ALLLAKSAES AEELSSSLTN SSDFDVKIYG WKIFLEN
//
