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Database: UniProt
Entry: A0A2G2WFF1_CAPBA
LinkDB: A0A2G2WFF1_CAPBA
Original site: A0A2G2WFF1_CAPBA 
ID   A0A2G2WFF1_CAPBA        Unreviewed;       253 AA.
AC   A0A2G2WFF1;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   31-JUL-2019, entry version 9.
DE   RecName: Full=Nicotinamide-nucleotide adenylyltransferase {ECO:0000256|RuleBase:RU362021};
DE            EC=2.7.7.1 {ECO:0000256|RuleBase:RU362021};
DE            EC=2.7.7.18 {ECO:0000256|RuleBase:RU362021};
DE   AltName: Full=Nicotinate-nucleotide adenylyltransferase {ECO:0000256|RuleBase:RU362021};
DE   Flags: Fragment;
GN   ORFNames=CQW23_18003 {ECO:0000313|EMBL:PHT43978.1};
OS   Capsicum baccatum (Peruvian pepper).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae;
OC   Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae;
OC   Capsiceae; Capsicum.
OX   NCBI_TaxID=33114 {ECO:0000313|EMBL:PHT43978.1, ECO:0000313|Proteomes:UP000224567};
RN   [1] {ECO:0000313|EMBL:PHT43978.1, ECO:0000313|Proteomes:UP000224567}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. PBC81 {ECO:0000313|Proteomes:UP000224567};
RC   TISSUE=Leaf {ECO:0000313|EMBL:PHT43978.1};
RX   PubMed=29089032; DOI=10.1186/s13059-017-1341-9;
RA   Kim S., Park J., Yeom S.I., Kim Y.M., Seo E., Kim K.T., Kim M.S.,
RA   Lee J.M., Cheong K., Shin H.S., Kim S.B., Han K., Lee J., Park M.,
RA   Lee H.A., Lee H.Y., Lee Y., Oh S., Lee J.H., Choi E., Choi E.,
RA   Lee S.E., Jeon J., Kim H., Choi G., Song H., Lee J., Lee S.C.,
RA   Kwon J.K., Lee H.Y., Koo N., Hong Y., Kim R.W., Kang W.H., Huh J.H.,
RA   Kang B.C., Yang T.J., Lee Y.H., Bennetzen J.L., Choi D.;
RT   "New reference genome sequences of hot pepper reveal the massive
RT   evolution of plant disease-resistance genes by retroduplication.";
RL   Genome Biol. 18:R210.1-R210.11(2017).
RN   [2] {ECO:0000313|EMBL:PHT43978.1, ECO:0000313|Proteomes:UP000224567}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. PBC81 {ECO:0000313|Proteomes:UP000224567};
RC   TISSUE=Leaf {ECO:0000313|EMBL:PHT43978.1};
RA   Kim S., Park J., Yeom S.-I., Kim Y.-M., Seo E., Kim K.-T., Kim M.-S.,
RA   Lee J.M., Cheong K., Shin H.-S., Kim S.-B., Han K., Lee J., Park M.,
RA   Lee H.-A., Lee H.-Y., Lee Y., Oh S., Lee J.H., Choi E., Choi E.,
RA   Lee S.E., Jeon J., Kim H., Choi G., Song H., Lee J., Lee S.-C.,
RA   Kwon J.-K., Lee H.-Y., Koo N., Hong Y., Kim R.W., Kang W.-H.,
RA   Huh J.H., Kang B.-C., Yang T.-J., Lee Y.-H., Bennetzen J.L., Choi D.;
RT   "Multiple reference genome sequences of hot pepper reveal the massive
RT   evolution of plant disease resistance genes by retroduplication.";
RL   J. Anim. Genet. bioRxivorg:115410-115410(2017).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H(+) + nicotinate beta-D-ribonucleotide = deamido-
CC         NAD(+) + diphosphate; Xref=Rhea:RHEA:22860, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57502,
CC         ChEBI:CHEBI:58437; EC=2.7.7.18;
CC         Evidence={ECO:0000256|RuleBase:RU362021};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + beta-nicotinamide D-ribonucleotide + H(+) =
CC         diphosphate + NAD(+); Xref=Rhea:RHEA:21360, ChEBI:CHEBI:14649,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019,
CC         ChEBI:CHEBI:57540; EC=2.7.7.1;
CC         Evidence={ECO:0000256|RuleBase:RU362021};
CC   -!- PATHWAY: Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from
CC       nicotinamide D-ribonucleotide: step 1/1.
CC       {ECO:0000256|RuleBase:RU362021}.
CC   -!- SIMILARITY: Belongs to the eukaryotic NMN adenylyltransferase
CC       family. {ECO:0000256|RuleBase:RU362021}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:PHT43978.1}.
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DR   EMBL; MLFT02000007; PHT43978.1; -; Genomic_DNA.
DR   UniPathway; UPA00253; UER00600.
DR   Proteomes; UP000224567; Chromosome 7.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000309; F:nicotinamide-nucleotide adenylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004515; F:nicotinate-nucleotide adenylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.40.50.620; -; 1.
DR   InterPro; IPR004821; Cyt_trans-like.
DR   InterPro; IPR005248; NadD/NMNAT.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   Pfam; PF01467; CTP_transf_like; 1.
DR   TIGRFAMs; TIGR00482; TIGR00482; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU362021};
KW   Complete proteome {ECO:0000313|Proteomes:UP000224567};
KW   NAD {ECO:0000256|RuleBase:RU362021};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362021};
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU362021,
KW   ECO:0000313|EMBL:PHT43978.1};
KW   Pyridine nucleotide biosynthesis {ECO:0000256|RuleBase:RU362021};
KW   Reference proteome {ECO:0000313|Proteomes:UP000224567};
KW   Transferase {ECO:0000256|RuleBase:RU362021,
KW   ECO:0000313|EMBL:PHT43978.1}.
FT   DOMAIN       39    219       CTP_transf_like. {ECO:0000259|Pfam:
FT                                PF01467}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:PHT43978.1}.
SQ   SEQUENCE   253 AA;  27856 MW;  FABEE0EC4ADF258D CRC64;
     GKTDIALPLD KLSLDLLKQV EGPSSPARRK RTSVILVSTG SFNPPTYMHL RCFELARDAL
     TSEGFCVIGG YMSPVNDAYK KKSLISAEHR VAMCELACKS SEFVMTDPWE AGQDSYQRTL
     AVLSRIKTAV GDGSLASIDD VKVMLVCGSD LLESFSTPGV WIPEQVRAIC RDFGLVCVRR
     GGQDVEKIIT NDDILNAYRK NIQVVDEVVP NGISSTGLRD CISKGLSVKY LTADEVIDYI
     KQHNLYKEQL SNN
//
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